PYROXD1 protein (human) - STRING database

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PYROXD1

Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily (500 aa)

Predicted Functional Partners:

DHX16

0.821

LSM2

0.806

LSM4

0.791

UPRT

0.753

FAM83G

0.723

MRPS27

0.680

PPP6R1

0.627

OR2L13

0.580

CCDC58

0.576

JAKMIP3

0.570

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC58	PYROXD1	ENSP00000291458	ENSP00000240651	Coiled-coil domain containing 58; Belongs to the CCDC58 family	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.576
DHX16	LSM2	ENSP00000365625	ENSP00000364813	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing; Belongs to the snRNP Sm proteins family	0.987
DHX16	LSM4	ENSP00000365625	ENSP00000469468	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3’-terminal U-tract of U6 snRNA; Belongs to the snRNP Sm proteins family	0.907
DHX16	PYROXD1	ENSP00000365625	ENSP00000240651	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.821
FAM83G	PYROXD1	ENSP00000373647	ENSP00000240651	Protein FAM83G; May regulate the bone morphogenetic proteins (BMP) pathway	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.723
JAKMIP3	OR2L13	ENSP00000298622	ENSP00000355434	Janus kinase and microtubule interacting protein 3	Olfactory receptor 2L13; Odorant receptor; Olfactory receptors, family 2	0.645
JAKMIP3	PYROXD1	ENSP00000298622	ENSP00000240651	Janus kinase and microtubule interacting protein 3	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.570
LSM2	DHX16	ENSP00000364813	ENSP00000365625	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing; Belongs to the snRNP Sm proteins family	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	0.987
LSM2	LSM4	ENSP00000364813	ENSP00000469468	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing; Belongs to the snRNP Sm proteins family	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3’-terminal U-tract of U6 snRNA; Belongs to the snRNP Sm proteins family	0.999
LSM2	PYROXD1	ENSP00000364813	ENSP00000240651	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing; Belongs to the snRNP Sm proteins family	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.806
LSM4	DHX16	ENSP00000469468	ENSP00000365625	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3’-terminal U-tract of U6 snRNA; Belongs to the snRNP Sm proteins family	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	0.907
LSM4	LSM2	ENSP00000469468	ENSP00000364813	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3’-terminal U-tract of U6 snRNA; Belongs to the snRNP Sm proteins family	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing; Belongs to the snRNP Sm proteins family	0.999
LSM4	PYROXD1	ENSP00000469468	ENSP00000240651	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3’-terminal U-tract of U6 snRNA; Belongs to the snRNP Sm proteins family	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.791
MRPS27	PYROXD1	ENSP00000426941	ENSP00000240651	28S ribosomal protein S27, mitochondrial; RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Involved also in positive regulation of cell proliferation and tumor cell growth	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.680
OR2L13	JAKMIP3	ENSP00000355434	ENSP00000298622	Olfactory receptor 2L13; Odorant receptor; Olfactory receptors, family 2	Janus kinase and microtubule interacting protein 3	0.645
OR2L13	PYROXD1	ENSP00000355434	ENSP00000240651	Olfactory receptor 2L13; Odorant receptor; Olfactory receptors, family 2	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.580
PPP6R1	PYROXD1	ENSP00000414202	ENSP00000240651	Serine/threonine-protein phosphatase 6 regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	0.627
PYROXD1	CCDC58	ENSP00000240651	ENSP00000291458	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	Coiled-coil domain containing 58; Belongs to the CCDC58 family	0.576
PYROXD1	DHX16	ENSP00000240651	ENSP00000365625	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily	0.821
PYROXD1	FAM83G	ENSP00000240651	ENSP00000373647	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Involved in cellular response to oxidative stress; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily	Protein FAM83G; May regulate the bone morphogenetic proteins (BMP) pathway	0.723

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