| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD22 | PLBD1 | ENSP00000360998 | ENSP00000240617 | Ankyrin repeat domain-containing protein 22; Ankyrin repeat domain containing | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.452 |
| GIPC3 | PLBD1 | ENSP00000319254 | ENSP00000240617 | PDZ domain-containing protein GIPC3; Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion; Deafness associated genes | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.459 |
| GLB1L | PLBD1 | ENSP00000295759 | ENSP00000240617 | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.596 |
| GLB1L | SERINC2 | ENSP00000295759 | ENSP00000362814 | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase | Serine incorporator 2; Belongs to the TDE1 family | 0.501 |
| GRTP1 | PLBD1 | ENSP00000364579 | ENSP00000240617 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.674 |
| PLBD1 | ANKRD22 | ENSP00000240617 | ENSP00000360998 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Ankyrin repeat domain-containing protein 22; Ankyrin repeat domain containing | 0.452 |
| PLBD1 | GIPC3 | ENSP00000240617 | ENSP00000319254 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | PDZ domain-containing protein GIPC3; Required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion; Deafness associated genes | 0.459 |
| PLBD1 | GLB1L | ENSP00000240617 | ENSP00000295759 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase | 0.596 |
| PLBD1 | GRTP1 | ENSP00000240617 | ENSP00000364579 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s) | 0.674 |
| PLBD1 | PLD2 | ENSP00000240617 | ENSP00000263088 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis; Phospholipases | 0.541 |
| PLBD1 | RPS7 | ENSP00000240617 | ENSP00000339095 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family | 0.505 |
| PLBD1 | SERINC2 | ENSP00000240617 | ENSP00000362814 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Serine incorporator 2; Belongs to the TDE1 family | 0.424 |
| PLBD1 | STK10 | ENSP00000240617 | ENSP00000176763 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Serine/threonine-protein kinase 10; Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase- mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | 0.513 |
| PLBD1 | TOP1 | ENSP00000240617 | ENSP00000354522 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5’-OH DNA strand. The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus remov [...] | 0.450 |
| PLBD1 | UQCRC1 | ENSP00000240617 | ENSP00000203407 | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | Cytochrome b-c1 complex subunit 1, mitochondrial; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1; M16 metallopeptidases | 0.525 |
| PLD2 | PLBD1 | ENSP00000263088 | ENSP00000240617 | Phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis; Phospholipases | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.541 |
| RPS7 | PLBD1 | ENSP00000339095 | ENSP00000240617 | 40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.505 |
| SERINC2 | GLB1L | ENSP00000362814 | ENSP00000295759 | Serine incorporator 2; Belongs to the TDE1 family | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase | 0.501 |
| SERINC2 | PLBD1 | ENSP00000362814 | ENSP00000240617 | Serine incorporator 2; Belongs to the TDE1 family | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.424 |
| STK10 | PLBD1 | ENSP00000176763 | ENSP00000240617 | Serine/threonine-protein kinase 10; Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase- mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | Phospholipase B-like 1; In view of the small size of the putative binding pocket, it has been proposed that it may act as an amidase or a peptidase (By similarity). Exhibits a weak phospholipase activity, acting on various phospholipids, including phosphatidylcholine, phosphatidylinositol, phosphatidylethanolamine and lysophospholipids | 0.513 |
