node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD10 | ZNF141 | ENSP00000273359 | ENSP00000240499 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.440 |
CREG2 | RELL1 | ENSP00000315203 | ENSP00000398778 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | RELT-like protein 1; RELT family; Belongs to the RELT family | 0.422 |
CREG2 | SFXN3 | ENSP00000315203 | ENSP00000224807 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | Sideroflexin-3; Potential iron transporter; Sideroflexins | 0.444 |
CREG2 | SREK1IP1 | ENSP00000315203 | ENSP00000427401 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | 0.447 |
CREG2 | ZNF141 | ENSP00000315203 | ENSP00000240499 | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.473 |
IQCE | ZNF141 | ENSP00000480715 | ENSP00000240499 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.440 |
MFSD7 | ZNF141 | ENSP00000384616 | ENSP00000240499 | Major facilitator superfamily domain containing 7 | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.440 |
MIPOL1 | ZNF141 | ENSP00000333539 | ENSP00000240499 | Mirror-image polydactyly 1 | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.576 |
RELL1 | CREG2 | ENSP00000398778 | ENSP00000315203 | RELT-like protein 1; RELT family; Belongs to the RELT family | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | 0.422 |
RELL1 | SREK1IP1 | ENSP00000398778 | ENSP00000427401 | RELT-like protein 1; RELT family; Belongs to the RELT family | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | 0.418 |
RELL1 | ZNF141 | ENSP00000398778 | ENSP00000240499 | RELT-like protein 1; RELT family; Belongs to the RELT family | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.440 |
SFXN3 | CREG2 | ENSP00000224807 | ENSP00000315203 | Sideroflexin-3; Potential iron transporter; Sideroflexins | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | 0.444 |
SFXN3 | SREK1IP1 | ENSP00000224807 | ENSP00000427401 | Sideroflexin-3; Potential iron transporter; Sideroflexins | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | 0.426 |
SFXN3 | ZNF141 | ENSP00000224807 | ENSP00000240499 | Sideroflexin-3; Potential iron transporter; Sideroflexins | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.446 |
SREK1IP1 | CREG2 | ENSP00000427401 | ENSP00000315203 | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | Protein CREG2; Cellular repressor of E1A stimulated genes 2 | 0.447 |
SREK1IP1 | RELL1 | ENSP00000427401 | ENSP00000398778 | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | RELT-like protein 1; RELT family; Belongs to the RELT family | 0.418 |
SREK1IP1 | SFXN3 | ENSP00000427401 | ENSP00000224807 | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | Sideroflexin-3; Potential iron transporter; Sideroflexins | 0.426 |
SREK1IP1 | ZNF141 | ENSP00000427401 | ENSP00000240499 | Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.473 |
TRIM28 | WHSC1 | ENSP00000253024 | ENSP00000372351 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Histone-lysine N-methyltransferase NSD2; Histone methyltransferase with histone H3 ’Lys-27’ (H3K27me) methyltransferase activity. Isoform 2 may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment | 0.440 |
TRIM28 | ZNF141 | ENSP00000253024 | ENSP00000240499 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.906 |