• Version:
  • 11.0 [archived version]
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IQCE IQCE MFSD7 MFSD7 TRIM28 TRIM28 WHSC1 WHSC1 ZNF141 ZNF141 MIPOL1 MIPOL1 SFXN3 SFXN3 SREK1IP1 SREK1IP1 CREG2 CREG2 ABHD10 ABHD10 RELL1 RELL1
"ZNF141" - Zinc finger protein 141 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF141Zinc finger protein 141; May be involved in transcriptional regulation as a repressor. Plays a role in limb development; Belongs to the krueppel C2H2-type zinc-finger protein family (474 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.906
MIPOL1
Mirror-image polydactyly 1 (442 aa)
     
   
  0.576
WHSC1
Histone-lysine N-methyltransferase NSD2; Histone methyltransferase with histone H3 ’Lys-27’ (H3K27me) methyltransferase activity. Isoform 2 may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment (1365 aa)
     
 
  0.542
SREK1IP1
Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival (155 aa)
           
  0.473
CREG2
Protein CREG2; Cellular repressor of E1A stimulated genes 2 (290 aa)
           
  0.473
SFXN3
Sideroflexin-3; Potential iron transporter; Sideroflexins (325 aa)
           
  0.446
IQCE
IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (702 aa)
           
  0.440
RELL1
RELT-like protein 1; RELT family; Belongs to the RELT family (271 aa)
           
  0.440
MFSD7
Major facilitator superfamily domain containing 7 (560 aa)
           
  0.440
ABHD10
Mycophenolic acid acyl-glucuronide esterase, mitochondrial; Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate; Belongs to the AB hydrolase superfamily (306 aa)
           
  0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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