| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DERL1 | FAM117A | ENSP00000259512 | ENSP00000240364 | Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for prot [...] | Protein FAM117A; Family with sequence similarity 117 member A | 0.493 |
| DERL1 | LRFN2 | ENSP00000259512 | ENSP00000345985 | Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for prot [...] | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | 0.496 |
| DLX3 | FAM117A | ENSP00000389870 | ENSP00000240364 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family | Protein FAM117A; Family with sequence similarity 117 member A | 0.471 |
| DLX3 | LRFN2 | ENSP00000389870 | ENSP00000345985 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | 0.408 |
| FAM117A | DERL1 | ENSP00000240364 | ENSP00000259512 | Protein FAM117A; Family with sequence similarity 117 member A | Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for prot [...] | 0.493 |
| FAM117A | DLX3 | ENSP00000240364 | ENSP00000389870 | Protein FAM117A; Family with sequence similarity 117 member A | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family | 0.471 |
| FAM117A | GMFG | ENSP00000240364 | ENSP00000472249 | Protein FAM117A; Family with sequence similarity 117 member A | Glia maturation factor gamma | 0.447 |
| FAM117A | LRFN2 | ENSP00000240364 | ENSP00000345985 | Protein FAM117A; Family with sequence similarity 117 member A | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | 0.721 |
| FAM117A | MON1B | ENSP00000240364 | ENSP00000248248 | Protein FAM117A; Family with sequence similarity 117 member A | MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family | 0.554 |
| FAM117A | OR2V2 | ENSP00000240364 | ENSP00000332185 | Protein FAM117A; Family with sequence similarity 117 member A | Olfactory receptor 2V2; Odorant receptor; Olfactory receptors, family 2 | 0.537 |
| FAM117A | SIDT2 | ENSP00000240364 | ENSP00000314023 | Protein FAM117A; Family with sequence similarity 117 member A | SID1 transmembrane family member 2; Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP- dependent manner, and degraded. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward R [...] | 0.444 |
| FAM117A | SLC46A3 | ENSP00000240364 | ENSP00000370192 | Protein FAM117A; Family with sequence similarity 117 member A | Solute carrier family 46 member 3; Belongs to the major facilitator superfamily. SLC46A family | 0.520 |
| FAM117A | TSSK6 | ENSP00000240364 | ENSP00000466477 | Protein FAM117A; Family with sequence similarity 117 member A | Testis-specific serine/threonine-protein kinase 6; Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity) | 0.609 |
| FAM117A | ZNF496 | ENSP00000240364 | ENSP00000294753 | Protein FAM117A; Family with sequence similarity 117 member A | Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.470 |
| GMFG | FAM117A | ENSP00000472249 | ENSP00000240364 | Glia maturation factor gamma | Protein FAM117A; Family with sequence similarity 117 member A | 0.447 |
| LRFN2 | DERL1 | ENSP00000345985 | ENSP00000259512 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for prot [...] | 0.496 |
| LRFN2 | DLX3 | ENSP00000345985 | ENSP00000389870 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family | 0.408 |
| LRFN2 | FAM117A | ENSP00000345985 | ENSP00000240364 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | Protein FAM117A; Family with sequence similarity 117 member A | 0.721 |
| LRFN2 | TSSK6 | ENSP00000345985 | ENSP00000466477 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | Testis-specific serine/threonine-protein kinase 6; Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling (By similarity) | 0.560 |
| LRFN2 | ZNF496 | ENSP00000345985 | ENSP00000294753 | Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity); Fibronectin type III domain containing | Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.401 |
