PCDHB10 protein (human) - STRING database

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PCDHB10

Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (800 aa)

Predicted Functional Partners:

CLVS2

0.548

C3orf52

0.480

ZNF343

0.477

SDCBP

0.439

SLC22A24

0.430

ZNF706

0.426

MDH1B

0.422

FAM46C

0.418

SLC25A2

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3orf52	CLVS2	ENSP00000399392	ENSP00000275162	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.698
C3orf52	PCDHB10	ENSP00000399392	ENSP00000239446	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.480
C3orf52	SLC22A24	ENSP00000399392	ENSP00000480336	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	Solute carrier family 22 member 24	0.501
C3orf52	ZNF343	ENSP00000399392	ENSP00000482819	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.530
CLVS2	C3orf52	ENSP00000275162	ENSP00000399392	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	0.698
CLVS2	PCDHB10	ENSP00000275162	ENSP00000239446	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.548
CLVS2	SLC22A24	ENSP00000275162	ENSP00000480336	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Solute carrier family 22 member 24	0.559
CLVS2	ZNF343	ENSP00000275162	ENSP00000482819	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.595
FAM46C	PCDHB10	ENSP00000358458	ENSP00000239446	Putative nucleotidyltransferase FAM46C; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.418
MDH1B	PCDHB10	ENSP00000363533	ENSP00000239446	Malate dehydrogenase 1B	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.422
PCDHB10	C3orf52	ENSP00000239446	ENSP00000399392	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	TPA-induced transmembrane protein; Chromosome 3 open reading frame 52	0.480
PCDHB10	CLVS2	ENSP00000239446	ENSP00000275162	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2)	0.548
PCDHB10	FAM46C	ENSP00000239446	ENSP00000358458	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Putative nucleotidyltransferase FAM46C; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase; Belongs to the FAM46 family	0.418
PCDHB10	MDH1B	ENSP00000239446	ENSP00000363533	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Malate dehydrogenase 1B	0.422
PCDHB10	SDCBP	ENSP00000239446	ENSP00000260130	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Syntenin-1; Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1- mediated SMAD2/3 activation and TGFB1-induced epithelial-to- mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6I [...]	0.439
PCDHB10	SLC22A24	ENSP00000239446	ENSP00000480336	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Solute carrier family 22 member 24	0.430
PCDHB10	SLC25A2	ENSP00000239446	ENSP00000239451	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Mitochondrial ornithine transporter 2; Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family	0.404
PCDHB10	ZNF343	ENSP00000239446	ENSP00000482819	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.477
PCDHB10	ZNF706	ENSP00000239446	ENSP00000430823	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	Zinc finger protein 706; Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4	0.426
SDCBP	PCDHB10	ENSP00000260130	ENSP00000239446	Syntenin-1; Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1- mediated SMAD2/3 activation and TGFB1-induced epithelial-to- mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6I [...]	Protocadherin beta-10; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins	0.439

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