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  • 11.0 [archived version]
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RAB3IP RAB3IP ZNF605 ZNF605 TIRAP TIRAP YIPF4 YIPF4 YIPF2 YIPF2 GTF3A GTF3A YIPF3 YIPF3 YIF1A YIF1A YIPF1 YIPF1 IER3IP1 IER3IP1 YIF1B YIF1B
"YIPF4" - Protein YIPF4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YIPF4Protein YIPF4; Involved in the maintenance of the Golgi structure; Belongs to the YIP1 family (244 aa)    
Predicted Functional Partners:
YIPF3
Protein YIPF3; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis; Yip1 domain containing (350 aa)
     
 
  0.927
YIPF2
Protein YIPF2; Yip1 domain family member 2 (316 aa)
     
 
  0.843
YIPF1
Protein YIPF1; Yip1 domain family member 1; Belongs to the YIP1 family (306 aa)
     
 
  0.814
YIF1A
Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family (293 aa)
     
 
  0.732
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity) (82 aa)
     
 
  0.669
RAB3IP
Rab-3A-interacting protein; Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface form [...] (476 aa)
           
  0.658
GTF3A
Transcription factor IIIA; Involved in ribosomal large subunit biogenesis. Binds the approximately 50 base pairs internal control region (ICR) of 5S ribosomal RNA genes. It is required for their RNA polymerase III-dependent transcription and may also maintain the transcription of other genes. Also binds the transcribed 5S RNA’s (By similarity); General transcription factors (365 aa)
           
  0.641
TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein; Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6; TIR domain containing (235 aa)
           
  0.589
YIF1B
Protein YIF1B; Yip1 interacting factor homolog B, membrane trafficking protein; Belongs to the YIF1 family (314 aa)
     
 
  0.587
ZNF605
Zinc finger protein 605; May be involved in transcriptional regulation; Zinc fingers C2H2-type (672 aa)
     
   
  0.576
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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