node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAT1 | ADAT2 | ENSP00000310015 | ENSP00000237283 | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala; Adenosine deaminases acting on RNA | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | 0.810 |
ADAT1 | ADAT3 | ENSP00000310015 | ENSP00000332448 | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala; Adenosine deaminases acting on RNA | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | 0.851 |
ADAT2 | ADAT1 | ENSP00000237283 | ENSP00000310015 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala; Adenosine deaminases acting on RNA | 0.810 |
ADAT2 | ADAT3 | ENSP00000237283 | ENSP00000332448 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | 0.999 |
ADAT2 | GNRH2 | ENSP00000237283 | ENSP00000245983 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | Progonadoliberin-2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family | 0.711 |
ADAT2 | GTF2H1 | ENSP00000237283 | ENSP00000265963 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | General transcription factor IIH subunit 1; Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II; General transcription factors | 0.671 |
ADAT2 | METTL1 | ENSP00000237283 | ENSP00000314441 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Methyltransferase like | 0.773 |
ADAT2 | RPSA | ENSP00000237283 | ENSP00000346067 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA | 0.756 |
ADAT2 | TRMT112 | ENSP00000237283 | ENSP00000438349 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on ’Gln-185’, using S-adenosyl L- methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading t [...] | 0.709 |
ADAT2 | TRMT6 | ENSP00000237283 | ENSP00000203001 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs- N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries | 0.735 |
ADAT2 | TRMT61A | ENSP00000237283 | ENSP00000374399 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)- methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs- N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries | 0.797 |
ADAT2 | WDR4 | ENSP00000237283 | ENSP00000381266 | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit; Belongs to the WD repeat TRM82 family | 0.788 |
ADAT3 | ADAT1 | ENSP00000332448 | ENSP00000310015 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA- Ala; Adenosine deaminases acting on RNA | 0.851 |
ADAT3 | ADAT2 | ENSP00000332448 | ENSP00000237283 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | 0.999 |
ADAT3 | METTL1 | ENSP00000332448 | ENSP00000314441 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Methyltransferase like | 0.784 |
ADAT3 | TRMT112 | ENSP00000332448 | ENSP00000438349 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on ’Gln-185’, using S-adenosyl L- methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading t [...] | 0.764 |
ADAT3 | TRMT6 | ENSP00000332448 | ENSP00000203001 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs- N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries | 0.777 |
ADAT3 | TRMT61A | ENSP00000332448 | ENSP00000374399 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Catalytic subunit of mRNA N(1)- methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs- N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries | 0.846 |
ADAT3 | WDR4 | ENSP00000332448 | ENSP00000381266 | Probable inactive tRNA-specific adenosine deaminase-like protein 3; Adenosine deaminase, tRNA specific 3; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit; Belongs to the WD repeat TRM82 family | 0.887 |
GNRH2 | ADAT2 | ENSP00000245983 | ENSP00000237283 | Progonadoliberin-2; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family | tRNA-specific adenosine deaminase 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs; Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily | 0.711 |