SPACA1 protein (human) - STRING database

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Score

SPACA1

Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion (294 aa)

Predicted Functional Partners:

ACRV1

0.827

SPACA4

0.786

DPY19L2

0.766

SPAG9

0.735

HIAT1

0.724

SPATA16

0.666

ZPBP

0.664

SPACA3

0.660

ZPBP2

0.649

SPESP1

0.618

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACRV1	SPACA1	ENSP00000432816	ENSP00000237201	Acrosomal vesicle protein 1	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	0.827
ACRV1	SPACA3	ENSP00000432816	ENSP00000269053	Acrosomal vesicle protein 1	Sperm acrosome membrane-associated protein 3; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro; Lysozymes, c-type	0.629
ACRV1	SPACA4	ENSP00000432816	ENSP00000312774	Acrosomal vesicle protein 1	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	0.717
ACRV1	SPAG9	ENSP00000432816	ENSP00000262013	Acrosomal vesicle protein 1	C-Jun-amino-terminal kinase-interacting protein 4; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction	0.552
ACRV1	ZPBP	ENSP00000432816	ENSP00000046087	Acrosomal vesicle protein 1	Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity); Immunoglobulin like domain containing	0.414
DPY19L2	HIAT1	ENSP00000315988	ENSP00000359171	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	Hippocampus abundant transcript 1	0.502
DPY19L2	SPACA1	ENSP00000315988	ENSP00000237201	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	0.766
DPY19L2	SPATA16	ENSP00000315988	ENSP00000341765	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion	0.867
DPY19L2	ZPBP	ENSP00000315988	ENSP00000046087	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity); Immunoglobulin like domain containing	0.564
HIAT1	DPY19L2	ENSP00000359171	ENSP00000315988	Hippocampus abundant transcript 1	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	0.502
HIAT1	SPACA1	ENSP00000359171	ENSP00000237201	Hippocampus abundant transcript 1	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	0.724
HIAT1	SPATA16	ENSP00000359171	ENSP00000341765	Hippocampus abundant transcript 1	Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion	0.644
HIAT1	ZPBP	ENSP00000359171	ENSP00000046087	Hippocampus abundant transcript 1	Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity); Immunoglobulin like domain containing	0.452
SPACA1	ACRV1	ENSP00000237201	ENSP00000432816	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Acrosomal vesicle protein 1	0.827
SPACA1	DPY19L2	ENSP00000237201	ENSP00000315988	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family	0.766
SPACA1	HIAT1	ENSP00000237201	ENSP00000359171	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Hippocampus abundant transcript 1	0.724
SPACA1	SPACA3	ENSP00000237201	ENSP00000269053	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Sperm acrosome membrane-associated protein 3; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro; Lysozymes, c-type	0.660
SPACA1	SPACA4	ENSP00000237201	ENSP00000312774	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization; LY6/PLAUR domain containing	0.786
SPACA1	SPAG9	ENSP00000237201	ENSP00000262013	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	C-Jun-amino-terminal kinase-interacting protein 4; The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction	0.735
SPACA1	SPATA16	ENSP00000237201	ENSP00000341765	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion	0.666

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