| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C6orf165 | CYB5R4 | ENSP00000358575 | ENSP00000358695 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | 0.719 |
| C6orf165 | DOPEY1 | ENSP00000358575 | ENSP00000237163 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | 0.774 |
| C6orf165 | HDHD1 | ENSP00000358575 | ENSP00000396452 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family | 0.790 |
| C6orf165 | PNPLA4 | ENSP00000358575 | ENSP00000370430 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing | 0.720 |
| C6orf165 | PRSS35 | ENSP00000358575 | ENSP00000358714 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Serine protease 35 | 0.783 |
| C6orf165 | UBE3D | ENSP00000358575 | ENSP00000358762 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | E3 ubiquitin-protein ligase E3D; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome | 0.826 |
| CYB5R4 | C6orf165 | ENSP00000358695 | ENSP00000358575 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | 0.719 |
| CYB5R4 | DOPEY1 | ENSP00000358695 | ENSP00000237163 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | 0.726 |
| CYB5R4 | HDHD1 | ENSP00000358695 | ENSP00000396452 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family | 0.683 |
| CYB5R4 | PNPLA4 | ENSP00000358695 | ENSP00000370430 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing | 0.630 |
| CYB5R4 | PRSS35 | ENSP00000358695 | ENSP00000358714 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | Serine protease 35 | 0.727 |
| CYB5R4 | UBE3D | ENSP00000358695 | ENSP00000358762 | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | E3 ubiquitin-protein ligase E3D; E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome | 0.719 |
| DOPEY1 | C6orf165 | ENSP00000237163 | ENSP00000358575 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | 0.774 |
| DOPEY1 | CYB5R4 | ENSP00000237163 | ENSP00000358695 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin | 0.726 |
| DOPEY1 | HDHD1 | ENSP00000237163 | ENSP00000396452 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family | 0.725 |
| DOPEY1 | MON2 | ENSP00000237163 | ENSP00000377250 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Armadillo-like helical domain containing | 0.923 |
| DOPEY1 | PNPLA4 | ENSP00000237163 | ENSP00000370430 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing | 0.707 |
| DOPEY1 | PRSS35 | ENSP00000237163 | ENSP00000358714 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Serine protease 35 | 0.724 |
| DOPEY1 | PUS7 | ENSP00000237163 | ENSP00000348722 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | Pseudouridylate synthase 7 | 0.730 |
| DOPEY1 | TRIP12 | ENSP00000237163 | ENSP00000373696 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes | E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardeless of the presence of lysine residues in target proteins. In normal cells, mediates ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A, a lysine-less tumor suppressor required for p53/TP53 activation under oncogenic stress. In cancer cells, however, isoform p19ARF/ARF and TRIP12 are located in [...] | 0.769 |
