| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B2M | CD160 | ENSP00000452780 | ENSP00000235933 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | 0.904 |
| B2M | HLA-A | ENSP00000452780 | ENSP00000379873 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, A-3 alpha chain; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.999 |
| B2M | HLA-B | ENSP00000452780 | ENSP00000399168 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, B-7 alpha chain; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.999 |
| B2M | HLA-C | ENSP00000452780 | ENSP00000365402 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, Cw-7 alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family | 0.999 |
| B2M | HLA-E | ENSP00000452780 | ENSP00000365817 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules; Belongs to the MHC class I family | 0.999 |
| B2M | HLA-F | ENSP00000452780 | ENSP00000259951 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.998 |
| B2M | HLA-G | ENSP00000452780 | ENSP00000412927 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | HLA class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells; Belongs to the MHC class I family | 0.998 |
| BTLA | CD160 | ENSP00000333919 | ENSP00000235933 | B- and T-lymphocyte attenuator; Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response; CD molecules | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | 0.796 |
| BTLA | LAG3 | ENSP00000333919 | ENSP00000203629 | B- and T-lymphocyte attenuator; Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response; CD molecules | Lymphocyte activation gene 3 protein; Involved in lymphocyte activation. Binds to HLA class-II antigens; CD molecules | 0.764 |
| BTLA | TNFRSF14 | ENSP00000333919 | ENSP00000347948 | B- and T-lymphocyte attenuator; Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response; CD molecules | Tumor necrosis factor receptor superfamily member 14; Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells; CD molecules | 0.999 |
| CD160 | B2M | ENSP00000235933 | ENSP00000452780 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation; Belongs to the beta-2-microglobulin family | 0.904 |
| CD160 | BTLA | ENSP00000235933 | ENSP00000333919 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | B- and T-lymphocyte attenuator; Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response; CD molecules | 0.796 |
| CD160 | HLA-A | ENSP00000235933 | ENSP00000379873 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, A-3 alpha chain; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.923 |
| CD160 | HLA-B | ENSP00000235933 | ENSP00000399168 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, B-7 alpha chain; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.915 |
| CD160 | HLA-C | ENSP00000235933 | ENSP00000365402 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, Cw-7 alpha chain; Involved in the presentation of foreign antigens to the immune system; Belongs to the MHC class I family | 0.960 |
| CD160 | HLA-E | ENSP00000235933 | ENSP00000365817 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, alpha chain E; Preferably binds to a peptide derived from the signal sequence of most HLA-A, -B, -C and -G molecules; Belongs to the MHC class I family | 0.932 |
| CD160 | HLA-F | ENSP00000235933 | ENSP00000259951 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system; C1-set domain containing | 0.919 |
| CD160 | HLA-G | ENSP00000235933 | ENSP00000412927 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | HLA class I histocompatibility antigen, alpha chain G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells; Belongs to the MHC class I family | 0.942 |
| CD160 | LAG3 | ENSP00000235933 | ENSP00000203629 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | Lymphocyte activation gene 3 protein; Involved in lymphocyte activation. Binds to HLA class-II antigens; CD molecules | 0.803 |
| CD160 | TNFRSF14 | ENSP00000235933 | ENSP00000347948 | CD160 antigen; Receptor showing broad specificity for both classical and non-classical MHC class I molecules | Tumor necrosis factor receptor superfamily member 14; Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells; CD molecules | 0.892 |
