• Version:
  • 11.0 [archived version]
STRINGSTRING
ELANE ELANE NPM2 NPM2 NFXL1 NFXL1 SNAI2 SNAI2 GCAT GCAT OSCP1 OSCP1 WDR54 WDR54 GYG2 GYG2 KIAA1328 KIAA1328 ANKRD13C ANKRD13C C7orf43 C7orf43
"OSCP1" - Protein OSCP1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
OSCP1Protein OSCP1; May be involved in drug clearance in the placenta (379 aa)    
Predicted Functional Partners:
GYG2
Glycogenin-2; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 (501 aa)
       
      0.816
WDR54
WD repeat-containing protein 54; WD repeat domain containing (334 aa)
       
      0.768
ELANE
Neutrophil elastase; Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (267 aa)
           
  0.711
NFXL1
NF-X1-type zinc finger protein NFXL1; Nuclear transcription factor, X-box binding like 1; Belongs to the NFX1 family (911 aa)
           
  0.620
GCAT
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; Glycine C-acetyltransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family (445 aa)
           
  0.617
NPM2
Nucleoplasmin-2; Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization; Belongs to the nucleoplasmin family (214 aa)
           
  0.511
C7orf43
Uncharacterized protein C7orf43; Chromosome 7 open reading frame 43 (580 aa)
           
  0.494
KIAA1328
Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes (577 aa)
           
  0.493
SNAI2
Zinc finger protein SNAI2; Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1- induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2- box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved in [...] (268 aa)
           
  0.480
ANKRD13C
Ankyrin repeat domain-containing protein 13C; Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER; Ankyrin repeat domain containing (541 aa)
           
  0.478
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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