C1orf21 protein (human) - STRING database

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C1orf21

Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21 (121 aa)

Predicted Functional Partners:

C5orf51

0.669

CEP162

0.598

C11orf57

0.556

ZNF19

0.543

SEMA3C

0.530

ELMSAN1

0.476

NKX2-8

0.475

CABIN1

0.435

NLRP13

0.426

CD97

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf57	C1orf21	ENSP00000376767	ENSP00000235307	Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.556
C11orf57	C5orf51	ENSP00000376767	ENSP00000371061	Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57	UPF0600 protein C5orf51; Chromosome 5 open reading frame 51; Belongs to the UPF0600 family	0.670
C1orf21	C11orf57	ENSP00000235307	ENSP00000376767	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57	0.556
C1orf21	C5orf51	ENSP00000235307	ENSP00000371061	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	UPF0600 protein C5orf51; Chromosome 5 open reading frame 51; Belongs to the UPF0600 family	0.669
C1orf21	CABIN1	ENSP00000235307	ENSP00000381364	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Calcineurin-binding protein cabin-1; May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it’s target genes	0.435
C1orf21	CD97	ENSP00000235307	ENSP00000242786	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	CD97 antigen; Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity); Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily	0.404
C1orf21	CEP162	ENSP00000235307	ENSP00000385215	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Centrosomal protein of 162 kDa; Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules; Belongs to the CEP162 family	0.598
C1orf21	ELMSAN1	ENSP00000235307	ENSP00000286523	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	ELM2 and Myb/SANT domain containing 1	0.476
C1orf21	NKX2-8	ENSP00000235307	ENSP00000258829	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Homeobox protein Nkx-2.8; NKL subclass homeoboxes and pseudogenes	0.475
C1orf21	NLRP13	ENSP00000235307	ENSP00000343891	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	NACHT, LRR and PYD domains-containing protein 13; Involved in inflammation; NLR family	0.426
C1orf21	SEMA3C	ENSP00000235307	ENSP00000265361	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Semaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity); I-set domain containing	0.530
C1orf21	ZNF19	ENSP00000235307	ENSP00000288177	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	Zinc finger protein 19; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.543
C5orf51	C11orf57	ENSP00000371061	ENSP00000376767	UPF0600 protein C5orf51; Chromosome 5 open reading frame 51; Belongs to the UPF0600 family	Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57	0.670
C5orf51	C1orf21	ENSP00000371061	ENSP00000235307	UPF0600 protein C5orf51; Chromosome 5 open reading frame 51; Belongs to the UPF0600 family	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.669
CABIN1	C1orf21	ENSP00000381364	ENSP00000235307	Calcineurin-binding protein cabin-1; May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it’s target genes	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.435
CD97	C1orf21	ENSP00000242786	ENSP00000235307	CD97 antigen; Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity); Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.404
CEP162	C1orf21	ENSP00000385215	ENSP00000235307	Centrosomal protein of 162 kDa; Required to promote assembly of the transition zone in primary cilia. Acts by specifically recognizing and binding the axonemal microtubule. Localizes to the distal ends of centrioles before ciliogenesis and directly binds to axonemal microtubule, thereby promoting and restricting transition zone formation specifically at the cilia base. Required to mediate CEP290 association with microtubules; Belongs to the CEP162 family	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.598
ELMSAN1	C1orf21	ENSP00000286523	ENSP00000235307	ELM2 and Myb/SANT domain containing 1	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.476
ELMSAN1	ZNF19	ENSP00000286523	ENSP00000288177	ELM2 and Myb/SANT domain containing 1	Zinc finger protein 19; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.492
NKX2-8	C1orf21	ENSP00000258829	ENSP00000235307	Homeobox protein Nkx-2.8; NKL subclass homeoboxes and pseudogenes	Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21	0.475

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