RMDN2 protein (human) - STRING database

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RMDN2

Regulator of microtubule dynamics 2; Belongs to the RMDN family (573 aa)

Predicted Functional Partners:

RMDN3

0.910

ZNF572

0.726

ZNF454

0.726

ZDHHC19

0.695

GCHFR

0.649

DNAJC17

0.642

RPUSD2

0.620

VAPB

0.620

SLC39A8

0.541

PTPN2

0.527

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC17	GCHFR	ENSP00000220496	ENSP00000260447	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	0.731
DNAJC17	RMDN2	ENSP00000220496	ENSP00000234195	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	Regulator of microtubule dynamics 2; Belongs to the RMDN family	0.642
DNAJC17	RMDN3	ENSP00000220496	ENSP00000260385	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis; Belongs to the RMDN family	0.670
DNAJC17	RPUSD2	ENSP00000220496	ENSP00000323288	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	RNA pseudouridylate synthase domain containing 2	0.799
GCHFR	DNAJC17	ENSP00000260447	ENSP00000220496	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	0.731
GCHFR	RMDN2	ENSP00000260447	ENSP00000234195	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	Regulator of microtubule dynamics 2; Belongs to the RMDN family	0.649
GCHFR	RMDN3	ENSP00000260447	ENSP00000260385	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis; Belongs to the RMDN family	0.703
GCHFR	RPUSD2	ENSP00000260447	ENSP00000323288	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	RNA pseudouridylate synthase domain containing 2	0.772
PTPN2	RMDN2	ENSP00000311857	ENSP00000234195	Tyrosine-protein phosphatase non-receptor type 2; Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the cytoplasm. Negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis. Plays a multifaceted and important role in the develop [...]	Regulator of microtubule dynamics 2; Belongs to the RMDN family	0.527
PTPN2	RMDN3	ENSP00000311857	ENSP00000260385	Tyrosine-protein phosphatase non-receptor type 2; Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the cytoplasm. Negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis. Plays a multifaceted and important role in the develop [...]	Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis; Belongs to the RMDN family	0.540
RMDN2	DNAJC17	ENSP00000234195	ENSP00000220496	Regulator of microtubule dynamics 2; Belongs to the RMDN family	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	0.642
RMDN2	GCHFR	ENSP00000234195	ENSP00000260447	Regulator of microtubule dynamics 2; Belongs to the RMDN family	GTP cyclohydrolase 1 feedback regulatory protein; Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine	0.649
RMDN2	PTPN2	ENSP00000234195	ENSP00000311857	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Tyrosine-protein phosphatase non-receptor type 2; Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. Also dephosphorylates non-receptor protein tyrosine kinases like JAK1, JAK2, JAK3, Src family kinases, STAT1, STAT3 and STAT6 either in the nucleus or the cytoplasm. Negatively regulates numerous signaling pathways and biological processes like hematopoiesis, inflammatory response, cell proliferation and differentiation, and glucose homeostasis. Plays a multifaceted and important role in the develop [...]	0.527
RMDN2	RMDN3	ENSP00000234195	ENSP00000260385	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis; Belongs to the RMDN family	0.910
RMDN2	RPUSD2	ENSP00000234195	ENSP00000323288	Regulator of microtubule dynamics 2; Belongs to the RMDN family	RNA pseudouridylate synthase domain containing 2	0.620
RMDN2	SLC39A8	ENSP00000234195	ENSP00000378310	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain; Belongs to the ZIP transporter (TC 2.A.5) family	0.541
RMDN2	VAPB	ENSP00000234195	ENSP00000417175	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Vesicle-associated membrane protein-associated protein B/C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	0.620
RMDN2	ZDHHC19	ENSP00000234195	ENSP00000296326	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Probable palmitoyltransferase ZDHHC19; Zinc finger DHHC-type containing 19; Belongs to the DHHC palmitoyltransferase family	0.695
RMDN2	ZNF454	ENSP00000234195	ENSP00000326249	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Zinc finger protein 454; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.726
RMDN2	ZNF572	ENSP00000234195	ENSP00000319305	Regulator of microtubule dynamics 2; Belongs to the RMDN family	Zinc finger protein 572; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.726

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