node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMMECR1 | C5orf15 | ENSP00000262844 | ENSP00000231512 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | 0.534 |
AMMECR1 | FIBCD1 | ENSP00000262844 | ENSP00000361413 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | 0.516 |
AMMECR1 | NLE1 | ENSP00000262844 | ENSP00000413572 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | Notchless protein homolog 1; Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity); Belongs to the NLE1/RSA4 family | 0.496 |
AMMECR1 | TMCO3 | ENSP00000262844 | ENSP00000389399 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation-proton antiporter 2 (CPA2) transporter (TC 2.A.37) family | 0.637 |
AMMECR1 | TMTC4 | ENSP00000262844 | ENSP00000343871 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.548 |
C5orf15 | AMMECR1 | ENSP00000231512 | ENSP00000262844 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.534 |
C5orf15 | FIBCD1 | ENSP00000231512 | ENSP00000361413 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | 0.552 |
C5orf15 | KRTAP15-1 | ENSP00000231512 | ENSP00000334866 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Keratin-associated protein 15-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.504 |
C5orf15 | KRTAP26-1 | ENSP00000231512 | ENSP00000353742 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Keratin-associated protein 26-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the PMG family | 0.513 |
C5orf15 | KRTAP27-1 | ENSP00000231512 | ENSP00000372286 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Keratin-associated protein 27-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.520 |
C5orf15 | KRTAP4-1 | ENSP00000231512 | ENSP00000381489 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Keratin-associated protein 4-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 4 family | 0.509 |
C5orf15 | KRTCAP3 | ENSP00000231512 | ENSP00000442400 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Keratinocyte associated protein 3 | 0.499 |
C5orf15 | NLE1 | ENSP00000231512 | ENSP00000413572 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Notchless protein homolog 1; Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity); Belongs to the NLE1/RSA4 family | 0.532 |
C5orf15 | TMCO3 | ENSP00000231512 | ENSP00000389399 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation-proton antiporter 2 (CPA2) transporter (TC 2.A.37) family | 0.637 |
C5orf15 | TMTC4 | ENSP00000231512 | ENSP00000343871 | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.563 |
FIBCD1 | AMMECR1 | ENSP00000361413 | ENSP00000262844 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | AMME syndrome candidate gene 1 protein; Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.516 |
FIBCD1 | C5orf15 | ENSP00000361413 | ENSP00000231512 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | Keratinocyte-associated transmembrane protein 2; Chromosome 5 open reading frame 15 | 0.552 |
FIBCD1 | NLE1 | ENSP00000361413 | ENSP00000413572 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | Notchless protein homolog 1; Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity); Belongs to the NLE1/RSA4 family | 0.487 |
FIBCD1 | TMCO3 | ENSP00000361413 | ENSP00000389399 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation-proton antiporter 2 (CPA2) transporter (TC 2.A.37) family | 0.520 |
FIBCD1 | TMTC4 | ENSP00000361413 | ENSP00000343871 | Fibrinogen C domain-containing protein 1; Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components; Fibrinogen C domain containing | Transmembrane and tetratricopeptide repeat containing 4; Belongs to the TMTC family | 0.525 |