• Version:
  • 11.0 [archived version]
STRINGSTRING
RNF180 RNF180 MYT1 MYT1 ZFHX4 ZFHX4 ZNF706 ZNF706 TENM2 TENM2 ZNF131 ZNF131 PCDHB15 PCDHB15 ZNF454 ZNF454 LRRC61 LRRC61 OR51B4 OR51B4 ZBED6CL ZBED6CL
"PCDHB15" - Protocadherin beta-15 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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PCDHB15Protocadherin beta-15; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (787 aa)    
Predicted Functional Partners:
ZNF706
Zinc finger protein 706; Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4 (76 aa)
           
  0.598
ZBED6CL
ZBED6 C-terminal-like protein; ZBED6 C-terminal like (236 aa)
           
  0.491
RNF180
E3 ubiquitin-protein ligase RNF180; E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2; Ring finger proteins (592 aa)
     
   
  0.490
ZNF131
Zinc finger protein 131; Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling; BTB domain containing (589 aa)
       
 
  0.489
TENM2
Teneurin-2; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion (By similarity). May function as a cellular signal transducer (2774 aa)
     
   
  0.474
MYT1
Myelin transcription factor 1; Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up- regulation of myelin gene transcription; Belongs to the MYT1 family (1121 aa)
     
   
  0.469
LRRC61
Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61 (259 aa)
           
  0.455
ZNF454
Zinc finger protein 454; May be involved in transcriptional regulation; Zinc fingers C2H2-type (522 aa)
       
 
  0.447
OR51B4
Olfactory receptor 51B4; Odorant receptor; Olfactory receptors, family 51 (310 aa)
           
  0.420
ZFHX4
Zinc finger homeobox protein 4; May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes (3616 aa)
           
  0.415
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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