• Version:
  • 11.0 [archived version]
STRINGSTRING
PCDHB12 PCDHB12 PCDHB16 PCDHB16 SCNN1D SCNN1D LRRIQ1 LRRIQ1 CCDC129 CCDC129 PCDHB7 PCDHB7 PFKFB4 PFKFB4 MCCC1 MCCC1 ERICH1 ERICH1 ZNF714 ZNF714 TRIM45 TRIM45
"PCDHB7" - Protocadherin beta-7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDHB7Protocadherin beta-7; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (793 aa)    
Predicted Functional Partners:
PCDHB16
Protocadherin beta-16; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (776 aa)
     
 
0.680
MCCC1
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism (725 aa)
           
  0.620
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; Synthesis and degradation of fructose 2,6-bisphosphate; In the C-terminal section; belongs to the phosphoglycerate mutase family (469 aa)
           
  0.575
CCDC129
Coiled-coil domain containing 129 (1062 aa)
           
  0.539
SCNN1D
Amiloride-sensitive sodium channel subunit delta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (802 aa)
           
  0.530
PCDHB12
Protocadherin beta-12; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (795 aa)
     
 
0.496
LRRIQ1
Leucine rich repeats and IQ motif containing 1 (1722 aa)
           
  0.467
TRIM45
Tripartite motif-containing protein 45; May act as a transcriptional repressor in mitogen- activated protein kinase signaling pathway; Ring finger proteins (580 aa)
       
 
  0.412
ERICH1
Glutamate-rich protein 1; Glutamate rich 1 (443 aa)
           
  0.411
ZNF714
Zinc finger protein 714; May be involved in transcriptional regulation; Zinc fingers C2H2-type (555 aa)
       
 
  0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]