| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTBD1 | ZBTB24 | ENSP00000261721 | ENSP00000230122 | BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.571 |
| CDCA7 | ZBTB24 | ENSP00000306968 | ENSP00000230122 | Cell division cycle-associated protein 7; Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.732 |
| DNAJC27 | PPIL6 | ENSP00000264711 | ENSP00000392257 | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling; DNAJ heat shock proteins | Peptidyl-prolyl cis-trans isomerase-like 6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases | 0.719 |
| DNAJC27 | ZBTB24 | ENSP00000264711 | ENSP00000230122 | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling; DNAJ heat shock proteins | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.703 |
| KIAA0020 | NOL12 | ENSP00000380982 | ENSP00000352021 | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family | 0.602 |
| KIAA0020 | RPL8 | ENSP00000380982 | ENSP00000262584 | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 60S ribosomal protein L8; Component of the large ribosomal subunit | 0.665 |
| KIAA0020 | RPP38 | ENSP00000380982 | ENSP00000478982 | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | 0.464 |
| KIAA0020 | ZBTB24 | ENSP00000380982 | ENSP00000230122 | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.726 |
| NOL12 | KIAA0020 | ENSP00000352021 | ENSP00000380982 | Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.602 |
| NOL12 | ZBTB24 | ENSP00000352021 | ENSP00000230122 | Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.536 |
| PPIL6 | DNAJC27 | ENSP00000392257 | ENSP00000264711 | Peptidyl-prolyl cis-trans isomerase-like 6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling; DNAJ heat shock proteins | 0.719 |
| PPIL6 | ZBTB24 | ENSP00000392257 | ENSP00000230122 | Peptidyl-prolyl cis-trans isomerase-like 6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.756 |
| RPL8 | KIAA0020 | ENSP00000262584 | ENSP00000380982 | 60S ribosomal protein L8; Component of the large ribosomal subunit | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.665 |
| RPL8 | RPP38 | ENSP00000262584 | ENSP00000478982 | 60S ribosomal protein L8; Component of the large ribosomal subunit | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | 0.588 |
| RPL8 | ZBTB24 | ENSP00000262584 | ENSP00000230122 | 60S ribosomal protein L8; Component of the large ribosomal subunit | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.708 |
| RPP38 | KIAA0020 | ENSP00000478982 | ENSP00000380982 | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity) | 0.464 |
| RPP38 | RPL8 | ENSP00000478982 | ENSP00000262584 | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | 60S ribosomal protein L8; Component of the large ribosomal subunit | 0.588 |
| RPP38 | UVRAG | ENSP00000478982 | ENSP00000348455 | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | UV radiation resistance-associated gene protein; Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex; the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P). During autophagy acts as regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturat [...] | 0.447 |
| RPP38 | ZBTB24 | ENSP00000478982 | ENSP00000230122 | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription; BTB domain containing | 0.675 |
| UVRAG | RPP38 | ENSP00000348455 | ENSP00000478982 | UV radiation resistance-associated gene protein; Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex; the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P). During autophagy acts as regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturat [...] | Ribonuclease P protein subunit p38; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus; Belongs to the eukaryotic ribosomal protein eL8 family | 0.447 |
