• Version:
  • 11.0 [archived version]
STRINGSTRING
GPR179 GPR179 VSIG8 VSIG8 LRRC15 LRRC15 GPBAR1 GPBAR1 B4GALT4 B4GALT4 PRR9 PRR9 GPRC5D GPRC5D C1orf204 C1orf204 GPR156 GPR156 SEC63 SEC63 VSTM4 VSTM4
"GPRC5D" - G protein-coupled receptor class C group 5 member D in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPRC5DG protein-coupled receptor class C group 5 member D (345 aa)    
Predicted Functional Partners:
PRR9
Proline-rich protein 9; Proline rich 9 (116 aa)
     
   
  0.624
B4GALT4
Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family (344 aa)
           
  0.611
GPR156
Probable G-protein coupled receptor 156; Orphan receptor; Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily (814 aa)
           
  0.596
C1orf204
Putative uncharacterized protein SNHG28; Chromosome 1 open reading frame 204 (235 aa)
     
   
  0.588
VSIG8
V-set and immunoglobulin domain containing 8; IgCAM CXADR-related subfamily (414 aa)
     
   
  0.582
GPR179
Probable G-protein coupled receptor 179; Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells; Belongs to the G-protein coupled receptor 3 family (2367 aa)
           
  0.560
VSTM4
V-set and transmembrane domain-containing protein 4; Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors; V-set domain containing (320 aa)
           
  0.543
SEC63
Translocation protein SEC63 homolog; Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane; DNAJ heat shock proteins (760 aa)
       
      0.534
LRRC15
Leucine-rich repeat-containing protein 15; Leucine rich repeat containing 15 (587 aa)
           
  0.527
GPBAR1
G-protein coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids (330 aa)
           
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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