• Version:
  • 11.0 [archived version]
STRINGSTRING
SCGB2B2 SCGB2B2 ETV4 ETV4 LCNL1 LCNL1 HMGN5 HMGN5 SCGB2A2 SCGB2A2 KRT19 KRT19 PIP PIP SCGB2A1 SCGB2A1 SCGB1D1 SCGB1D1 SCGB1D2 SCGB1D2 MUCL1 MUCL1
"SCGB2A2" - Mammaglobin-A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCGB2A2Mammaglobin-A; Secretoglobin family 2A member 2; Secretoglobins (93 aa)    
Predicted Functional Partners:
SCGB1D2
Secretoglobin family 1D member 2; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins (90 aa)
     
 
  0.978
MUCL1
Mucin-like protein 1; May play a role as marker for the diagnosis of metastatic breast cancer (90 aa)
     
   
  0.954
SCGB1D1
Secretoglobin family 1D member 1; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Secretoglobins (90 aa)
     
   
  0.846
PIP
Prolactin induced protein; Belongs to the PIP family (146 aa)
     
   
  0.787
HMGN5
High mobility group nucleosome-binding domain-containing protein 5; Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction; Belongs to the HMGN family (282 aa)
           
  0.664
ETV4
ETS translocation variant 4; Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5’[AC]GGA[AT]GT-3’; ETS transcription factor family (484 aa)
           
  0.641
KRT19
Keratin, type I cytoskeletal 19; Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Keratins, type I (400 aa)
           
  0.584
SCGB2A1
Mammaglobin-B; May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones; Belongs to the secretoglobin family. Lipophilin subfamily (95 aa)
     
   
0.568
SCGB2B2
Secretoglobin family 2B member 2; Secretoglobins (96 aa)
           
  0.558
LCNL1
Lipocalin-like 1 protein; Lipocalin like 1; Belongs to the calycin superfamily. Lipocalin family (164 aa)
           
  0.555
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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