GIMAP2 protein (human) - STRING database

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GIMAP2

GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself (337 aa)

Predicted Functional Partners:

AIG1

0.580

GIMAP7

0.558

UBAC2

0.553

STOM

0.534

TOR1B

0.519

KLRC4

0.480

TMEM200B

0.473

VMA21

0.465

C22orf23

0.430

CCDC134

0.426

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIG1	GIMAP2	ENSP00000350509	ENSP00000223293	Androgen-induced gene 1 protein; May play a role in androgen-regulated growth of hair follicles; Belongs to the AIG1 family	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.580
AIG1	GIMAP7	ENSP00000350509	ENSP00000315474	Androgen-induced gene 1 protein; May play a role in androgen-regulated growth of hair follicles; Belongs to the AIG1 family	GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits; GTPases, IMAP	0.420
C22orf23	GIMAP2	ENSP00000249079	ENSP00000223293	UPF0193 protein EVG1; Chromosome 22 open reading frame 23	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.430
C22orf23	TMEM200B	ENSP00000249079	ENSP00000428544	UPF0193 protein EVG1; Chromosome 22 open reading frame 23	Transmembrane protein 200B	0.618
CCDC134	GIMAP2	ENSP00000255784	ENSP00000223293	Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.426
GIMAP2	AIG1	ENSP00000223293	ENSP00000350509	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Androgen-induced gene 1 protein; May play a role in androgen-regulated growth of hair follicles; Belongs to the AIG1 family	0.580
GIMAP2	C22orf23	ENSP00000223293	ENSP00000249079	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	UPF0193 protein EVG1; Chromosome 22 open reading frame 23	0.430
GIMAP2	CCDC134	ENSP00000223293	ENSP00000255784	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family	0.426
GIMAP2	GIMAP7	ENSP00000223293	ENSP00000315474	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits; GTPases, IMAP	0.558
GIMAP2	KLRC4	ENSP00000223293	ENSP00000310216	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	NKG2-F type II integral membrane protein; May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells; Killer cell lectin like receptors	0.480
GIMAP2	STOM	ENSP00000223293	ENSP00000286713	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity; Belongs to the band 7/mec-2 family	0.534
GIMAP2	TMEM200B	ENSP00000223293	ENSP00000428544	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Transmembrane protein 200B	0.473
GIMAP2	TOR1B	ENSP00000223293	ENSP00000259339	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Torsin-1B; May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity. May have a redundant function with TOR1A in non-neural tissues; Belongs to the ClpA/ClpB family. Torsin subfamily	0.519
GIMAP2	UBAC2	ENSP00000223293	ENSP00000383911	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets; Rhomboid family	0.553
GIMAP2	VMA21	ENSP00000223293	ENSP00000333255	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum	0.465
GIMAP7	AIG1	ENSP00000315474	ENSP00000350509	GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits; GTPases, IMAP	Androgen-induced gene 1 protein; May play a role in androgen-regulated growth of hair follicles; Belongs to the AIG1 family	0.420
GIMAP7	GIMAP2	ENSP00000315474	ENSP00000223293	GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits; GTPases, IMAP	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.558
KLRC4	GIMAP2	ENSP00000310216	ENSP00000223293	NKG2-F type II integral membrane protein; May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells; Killer cell lectin like receptors	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.480
KLRC4	UBAC2	ENSP00000310216	ENSP00000383911	NKG2-F type II integral membrane protein; May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells; Killer cell lectin like receptors	Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets; Rhomboid family	0.473
STOM	GIMAP2	ENSP00000286713	ENSP00000223293	Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity; Belongs to the band 7/mec-2 family	GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself	0.534

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