• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF804A ZNF804A EBLN1 EBLN1 ZC3H4 ZC3H4 DIDO1 DIDO1 KIAA0907 KIAA0907 YAE1D1 YAE1D1 MMS19 MMS19 CIAPIN1 CIAPIN1 ORAOV1 ORAOV1 ABCE1 ABCE1 NARFL NARFL
"YAE1D1" - Yae1 domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YAE1D1Yae1 domain containing 1 (226 aa)    
Predicted Functional Partners:
ORAOV1
Oral cancer overexpressed 1 (137 aa)
     
 
  0.963
ABCE1
ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly; Belongs to the ABC transporter superfamily. ABCE family (599 aa)
     
 
  0.804
ZC3H4
Zinc finger CCCH domain-containing protein 4; Armadillo-like helical domain containing (1303 aa)
           
  0.659
DIDO1
Death-inducer obliterator 1; Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development; PHD finger proteins (2240 aa)
           
  0.628
MMS19
MMS19 nucleotide excision repair protein homolog; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle [...] (1030 aa)
           
  0.626
NARFL
Cytosolic Fe-S cluster assembly factor NARFL; Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect; Belongs to the NARF family (476 aa)
           
  0.613
ZNF804A
Zinc finger protein 804A (1209 aa)
           
  0.612
EBLN1
Endogenous Bornavirus-like nucleoprotein 1; May act as an RNA-binding protein. Highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes (By similarity) (366 aa)
           
  0.586
KIAA0907
Protein BLOM7; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches; Belongs to the BLOM7 family (614 aa)
           
  0.586
CIAPIN1
Anamorsin; Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1 (312 aa)
           
  0.578
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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