• Version:
  • 11.0 [archived version]
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DCAF10 DCAF10 C17orf75 C17orf75 FKBP6 FKBP6 FKBP14 FKBP14 RSPRY1 RSPRY1 PIN1 PIN1 EAF1 EAF1 METTL6 METTL6 FAM192A FAM192A SNX20 SNX20 EFCAB1 EFCAB1
"FKBP14" - Peptidyl-prolyl cis-trans isomerase FKBP14 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FKBP14Peptidyl-prolyl cis-trans isomerase FKBP14; PPIases accelerate the folding of proteins during protein synthesis; EF-hand domain containing (211 aa)    
Predicted Functional Partners:
EFCAB1
EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 (211 aa)
       
 
  0.797
RSPRY1
Ring finger and SPRY domain containing 1 (576 aa)
           
  0.762
FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be re [...] (327 aa)
   
     
  0.757
FAM192A
Protein FAM192A; Family with sequence similarity 192 member A (254 aa)
           
  0.733
METTL6
Methyltransferase-like protein 6; Probable methyltransferase (284 aa)
     
   
  0.724
DCAF10
DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (559 aa)
     
   
  0.721
SNX20
Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion (316 aa)
           
  0.715
C17orf75
Protein Njmu-R1; May have a role in spermatogenesis (396 aa)
           
  0.714
EAF1
ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family (268 aa)
           
  0.703
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr- Pro) motifs. By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes. Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Down-regulates kinase activity of BTK. Can transactivate multiple [...] (163 aa)
     
 
  0.703
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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