| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARL6IP4 | CCDC9 | ENSP00000313422 | ENSP00000221922 | ADP-ribosylation factor-like protein 6-interacting protein 4; Involved in modulating alternative pre-mRNA splicing with either 5’ distal site activation or preferential use of 3’ proximal site. In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA | Coiled-coil domain containing 9 | 0.547 |
| B4GALNT4 | CCDC9 | ENSP00000328277 | ENSP00000221922 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family | Coiled-coil domain containing 9 | 0.589 |
| B4GALNT4 | MXRA7 | ENSP00000328277 | ENSP00000348050 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | 0.673 |
| B4GALNT4 | ST8SIA1 | ENSP00000328277 | ENSP00000379353 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family | Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid; Sialyltransferases | 0.405 |
| CCDC9 | ARL6IP4 | ENSP00000221922 | ENSP00000313422 | Coiled-coil domain containing 9 | ADP-ribosylation factor-like protein 6-interacting protein 4; Involved in modulating alternative pre-mRNA splicing with either 5’ distal site activation or preferential use of 3’ proximal site. In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA | 0.547 |
| CCDC9 | B4GALNT4 | ENSP00000221922 | ENSP00000328277 | Coiled-coil domain containing 9 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family | 0.589 |
| CCDC9 | CMSS1 | ENSP00000221922 | ENSP00000410396 | Coiled-coil domain containing 9 | Protein CMSS1; Cms1 ribosomal small subunit homolog | 0.534 |
| CCDC9 | MDC1 | ENSP00000221922 | ENSP00000365588 | Coiled-coil domain containing 9 | Mediator of DNA damage checkpoint protein 1; Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by ’Ser-139’ phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be a [...] | 0.693 |
| CCDC9 | MXRA7 | ENSP00000221922 | ENSP00000348050 | Coiled-coil domain containing 9 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | 0.517 |
| CCDC9 | PNN | ENSP00000221922 | ENSP00000216832 | Coiled-coil domain containing 9 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | 0.798 |
| CCDC9 | SSUH2 | ENSP00000221922 | ENSP00000439378 | Coiled-coil domain containing 9 | Protein SSUH2 homolog; Plays a role in odontogenesis | 0.539 |
| CCDC9 | ST8SIA1 | ENSP00000221922 | ENSP00000379353 | Coiled-coil domain containing 9 | Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid; Sialyltransferases | 0.676 |
| CCDC9 | THOC7 | ENSP00000221922 | ENSP00000295899 | Coiled-coil domain containing 9 | THO complex subunit 7 homolog; Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm vi [...] | 0.638 |
| CCDC9 | WSB2 | ENSP00000221922 | ENSP00000409131 | Coiled-coil domain containing 9 | WD repeat and SOCS box-containing protein 2; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; WD repeat domain containing | 0.558 |
| CMSS1 | CCDC9 | ENSP00000410396 | ENSP00000221922 | Protein CMSS1; Cms1 ribosomal small subunit homolog | Coiled-coil domain containing 9 | 0.534 |
| MDC1 | CCDC9 | ENSP00000365588 | ENSP00000221922 | Mediator of DNA damage checkpoint protein 1; Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by ’Ser-139’ phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be a [...] | Coiled-coil domain containing 9 | 0.693 |
| MXRA7 | B4GALNT4 | ENSP00000348050 | ENSP00000328277 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family | 0.673 |
| MXRA7 | CCDC9 | ENSP00000348050 | ENSP00000221922 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 | Coiled-coil domain containing 9 | 0.517 |
| PNN | CCDC9 | ENSP00000216832 | ENSP00000221922 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | Coiled-coil domain containing 9 | 0.798 |
| PNN | WSB2 | ENSP00000216832 | ENSP00000409131 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5’CAGGTG-3’. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulatio [...] | WD repeat and SOCS box-containing protein 2; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; WD repeat domain containing | 0.661 |
