node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BHMG1 | DMWD | ENSP00000402674 | ENSP00000270223 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | 0.564 |
BHMG1 | RSPH6A | ENSP00000402674 | ENSP00000221538 | Basic helix-loop-helix and HMG box domain-containing protein 1 | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.571 |
DMWD | BHMG1 | ENSP00000270223 | ENSP00000402674 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Basic helix-loop-helix and HMG box domain-containing protein 1 | 0.564 |
DMWD | RSPH6A | ENSP00000270223 | ENSP00000221538 | Dystrophia myotonica WD repeat-containing protein; DM1 locus, WD repeat containing | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.813 |
MAATS1 | RSPH3 | ENSP00000273390 | ENSP00000252655 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.855 |
MAATS1 | RSPH6A | ENSP00000273390 | ENSP00000221538 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.587 |
MAATS1 | RSU1 | ENSP00000273390 | ENSP00000367154 | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | 0.485 |
PHF12 | RSPH3 | ENSP00000329933 | ENSP00000252655 | PHD finger protein 12; Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.416 |
PHF12 | RSPH6A | ENSP00000329933 | ENSP00000221538 | PHD finger protein 12; Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.587 |
PHF12 | RSU1 | ENSP00000329933 | ENSP00000367154 | PHD finger protein 12; Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA | Ras suppressor protein 1; Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro | 0.445 |
PIWIL2 | RSPH1 | ENSP00000349208 | ENSP00000291536 | Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent re [...] | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | 0.657 |
PIWIL2 | RSPH6A | ENSP00000349208 | ENSP00000221538 | Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent re [...] | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.583 |
RSPH1 | PIWIL2 | ENSP00000291536 | ENSP00000349208 | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | Piwi-like protein 2; Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent re [...] | 0.657 |
RSPH1 | RSPH3 | ENSP00000291536 | ENSP00000252655 | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.825 |
RSPH1 | RSPH6A | ENSP00000291536 | ENSP00000221538 | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.599 |
RSPH1 | RSPH9 | ENSP00000291536 | ENSP00000361238 | Radial spoke head 1 homolog; May play an important role in male meiosis (By similarity). It is necessary for proper building of the axonemal central pair and radial spokes | Radial spoke head 9 homolog | 0.806 |
RSPH10B | RSPH3 | ENSP00000385443 | ENSP00000252655 | Radial spoke head 10 homolog B | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.555 |
RSPH10B | RSPH6A | ENSP00000385443 | ENSP00000221538 | Radial spoke head 10 homolog B | Radial spoke head 6 homolog A; Belongs to the flagellar radial spoke RSP4/6 family | 0.587 |
RSPH10B | RSPH9 | ENSP00000385443 | ENSP00000361238 | Radial spoke head 10 homolog B | Radial spoke head 9 homolog | 0.531 |
RSPH3 | MAATS1 | ENSP00000252655 | ENSP00000273390 | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | Cilia- and flagella-associated protein 91; May regulate cilium motility through its role in the assembly of the axonemal radial spokes | 0.855 |