node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C6 | PPP1R37 | ENSP00000263413 | ENSP00000221462 | Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Complement system | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.499 |
CEACAM16 | PPP1R37 | ENSP00000466561 | ENSP00000221462 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, it may play a role in maintaining the integrity of the tectorial membrane; Belongs to the immunoglobulin superfamily. CEA family | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.437 |
CREBL2 | MANSC1 | ENSP00000228865 | ENSP00000438205 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | MANSC domain containing 1 | 0.634 |
CREBL2 | MS4A15 | ENSP00000228865 | ENSP00000386022 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | 0.441 |
CREBL2 | PPM1N | ENSP00000228865 | ENSP00000397050 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Protein phosphatase, Mg2+/Mn2+ dependent 1N | 0.430 |
CREBL2 | PPP1R37 | ENSP00000228865 | ENSP00000221462 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.440 |
FXYD2 | PPP1R37 | ENSP00000292079 | ENSP00000221462 | Sodium/potassium-transporting ATPase subunit gamma; May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase; Belongs to the FXYD family | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.426 |
MANSC1 | CREBL2 | ENSP00000438205 | ENSP00000228865 | MANSC domain containing 1 | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.634 |
MANSC1 | MS4A15 | ENSP00000438205 | ENSP00000386022 | MANSC domain containing 1 | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | 0.506 |
MANSC1 | PPM1N | ENSP00000438205 | ENSP00000397050 | MANSC domain containing 1 | Protein phosphatase, Mg2+/Mn2+ dependent 1N | 0.476 |
MANSC1 | PPP1R37 | ENSP00000438205 | ENSP00000221462 | MANSC domain containing 1 | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.495 |
MS4A15 | CREBL2 | ENSP00000386022 | ENSP00000228865 | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.441 |
MS4A15 | MANSC1 | ENSP00000386022 | ENSP00000438205 | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | MANSC domain containing 1 | 0.506 |
MS4A15 | PPM1N | ENSP00000386022 | ENSP00000397050 | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | Protein phosphatase, Mg2+/Mn2+ dependent 1N | 0.581 |
MS4A15 | PPP1R37 | ENSP00000386022 | ENSP00000221462 | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.579 |
PPM1N | CREBL2 | ENSP00000397050 | ENSP00000228865 | Protein phosphatase, Mg2+/Mn2+ dependent 1N | cAMP-responsive element-binding protein-like 2; Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor; Belongs to the bZIP family. ATF subfamily | 0.430 |
PPM1N | MANSC1 | ENSP00000397050 | ENSP00000438205 | Protein phosphatase, Mg2+/Mn2+ dependent 1N | MANSC domain containing 1 | 0.476 |
PPM1N | MS4A15 | ENSP00000397050 | ENSP00000386022 | Protein phosphatase, Mg2+/Mn2+ dependent 1N | Membrane-spanning 4-domains subfamily A member 15; May be involved in signal transduction as a component of a multimeric receptor complex; Membrane spanning 4-domains | 0.581 |
PPM1N | PPP1R37 | ENSP00000397050 | ENSP00000221462 | Protein phosphatase, Mg2+/Mn2+ dependent 1N | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | 0.573 |
PPP1R37 | C6 | ENSP00000221462 | ENSP00000263413 | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family | Complement component C6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells; Complement system | 0.499 |