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STRINGSTRING
MFSD2B MFSD2B C16orf59 C16orf59 BCAS3 BCAS3 ZNF311 ZNF311 KIF17 KIF17 C16orf70 C16orf70 CBFB CBFB ZFAND2B ZFAND2B C1orf64 C1orf64 FAM192A FAM192A CCDC74B CCDC74B
"C16orf70" - UPF0183 protein C16orf70 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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C16orf70UPF0183 protein C16orf70; Chromosome 16 open reading frame 70; Belongs to the UPF0183 family (422 aa)    
Predicted Functional Partners:
BCAS3
Breast carcinoma-amplified sequence 3; Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin; Belongs to the BCAS3 family (928 aa)
      
      0.824
KIF17
Kinesin-like protein KIF17; Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family (1029 aa)
        
 
  0.700
CCDC74B
Coiled-coil domain containing 74B (380 aa)
            
  0.674
C16orf59
Uncharacterized protein C16orf59; Chromosome 16 open reading frame 59 (433 aa)
            
  0.634
C1orf64
Steroid receptor-associated and regulated protein; May regulate the transcriptional function of androgen and estrogen receptors (169 aa)
            
  0.623
MFSD2B
Major facilitator superfamily domain-containing protein 2B; Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets. Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC) (By similarity) (497 aa)
            
  0.588
CBFB
Core-binding factor subunit beta; CBF binds to the core site, 5’-PYGPYGGT-3’, of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM- CSF promoters. CBFB enhances DNA binding by RUNX1; Belongs to the CBF-beta family (187 aa)
  
            0.579
ZNF311
Zinc finger protein 311; May be involved in transcriptional regulation; Zinc fingers C2H2-type (666 aa)
            
  0.560
FAM192A
Protein FAM192A; Family with sequence similarity 192 member A (254 aa)
            
  0.551
ZFAND2B
Zinc finger AN1-type containing 2B (257 aa)
            
  0.540
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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