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  • 11.0 [archived version]
STRINGSTRING
MAP3K15 MAP3K15 GPR112 GPR112 ZNF280C ZNF280C FRMD7 FRMD7 HDHD1 HDHD1 SLC25A43 SLC25A43 RNF113A RNF113A CXorf56 CXorf56 SEPT6 SEPT6 DOCK11 DOCK11 NUP62CL NUP62CL
"SLC25A43" - Solute carrier family 25 member 43 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SLC25A43Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family (341 aa)    
Predicted Functional Partners:
SEPT6
Septin-6; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation; Septins (434 aa)
     
   
  0.779
RNF113A
RING finger protein 113A; Spliceosomal Bact complex; Ring finger proteins (343 aa)
     
   
  0.751
MAP3K15
Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily (1313 aa)
           
  0.684
GPR112
Adhesion G-protein coupled receptor G4; Orphan receptor; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (3080 aa)
     
   
  0.654
FRMD7
FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability; FERM domain containing (714 aa)
           
  0.637
CXorf56
UPF0428 protein CXorf56; Chromosome X open reading frame 56; Spliceosomal C complex (208 aa)
     
   
  0.636
DOCK11
Dedicator of cytokinesis protein 11; Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42; Belongs to the DOCK family (2073 aa)
     
   
  0.627
ZNF280C
Zinc finger protein 280C; May function as a transcription factor (737 aa)
     
   
  0.606
NUP62CL
Nucleoporin-62 C-terminal-like protein; Nucleoporin 62 C-terminal like; Belongs to the nucleoporin NSP1/NUP62 family (184 aa)
     
   
  0.590
HDHD1
Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family (251 aa)
     
   
  0.549
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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