TMED8 protein (human) - STRING database

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TMED8

Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing (325 aa)

Predicted Functional Partners:

NOXRED1

0.680

C14orf178

0.669

SAMD15

0.630

TMEM63C

0.591

GSTZ1

0.548

AASDH

0.539

ARL6IP6

0.533

ADCK1

0.497

NGB

0.494

BLZF1

0.459

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AASDH	TMED8	ENSP00000205214	ENSP00000216468	Acyl-CoA synthetase family member 4; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA; Acyl-CoA synthetase family	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.539
ADCK1	C14orf178	ENSP00000238561	ENSP00000348145	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	0.585
ADCK1	NOXRED1	ENSP00000238561	ENSP00000370215	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.668
ADCK1	SAMD15	ENSP00000238561	ENSP00000216471	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Sterile alpha motif domain containing 15	0.556
ADCK1	TMED8	ENSP00000238561	ENSP00000216468	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.497
ARL6IP6	TMED8	ENSP00000315357	ENSP00000216468	ADP ribosylation factor like GTPase 6 interacting protein 6; Belongs to the ARL6IP6 family	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.533
BLZF1	TMED8	ENSP00000356782	ENSP00000216468	Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.459
C14orf178	ADCK1	ENSP00000348145	ENSP00000238561	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	0.585
C14orf178	NOXRED1	ENSP00000348145	ENSP00000370215	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	0.765
C14orf178	SAMD15	ENSP00000348145	ENSP00000216471	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Sterile alpha motif domain containing 15	0.679
C14orf178	TMED8	ENSP00000348145	ENSP00000216468	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.669
GSTZ1	TMED8	ENSP00000216465	ENSP00000216468	Maleylacetoacetate isomerase; Bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4- nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T- butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid; Soluble glutathione S-transferases	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.548
GSTZ1	TMEM63C	ENSP00000216465	ENSP00000298351	Maleylacetoacetate isomerase; Bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4- nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T- butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid; Soluble glutathione S-transferases	Calcium permeable stress-gated cation channel 1; Acts as an osmosensitive calcium-permeable cation channel	0.696
NGB	TMED8	ENSP00000298352	ENSP00000216468	Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.494
NGB	TMEM63C	ENSP00000298352	ENSP00000298351	Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis	Calcium permeable stress-gated cation channel 1; Acts as an osmosensitive calcium-permeable cation channel	0.498
NOXRED1	ADCK1	ENSP00000370215	ENSP00000238561	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	0.668
NOXRED1	C14orf178	ENSP00000370215	ENSP00000348145	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178	0.765
NOXRED1	SAMD15	ENSP00000370215	ENSP00000216471	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Sterile alpha motif domain containing 15	0.731
NOXRED1	TMED8	ENSP00000370215	ENSP00000216468	NADP-dependent oxidoreductase domain-containing protein 1; Probable oxidoreductase	Protein TMED8; Transmembrane p24 trafficking protein family member 8; GOLD domain containing	0.680
SAMD15	ADCK1	ENSP00000216471	ENSP00000238561	Sterile alpha motif domain containing 15	Uncharacterized aarF domain-containing protein kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr)	0.556

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