• Version:
  • 11.0 [archived version]
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RIMBP3 RIMBP3 RIMBP3B RIMBP3B ATP5L2 ATP5L2 GSTT2B GSTT2B POTEH POTEH SLC35E4 SLC35E4 DDTL DDTL CECR6 CECR6 TST TST BPTF BPTF AMDHD1 AMDHD1
"DDTL" - D-dopachrome decarboxylase-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
DDTLD-dopachrome decarboxylase-like protein; May have lyase activity (134 aa)    
Predicted Functional Partners:
SLC35E4
Solute carrier family 35 member E4; Putative transporter; Solute carriers (350 aa)
           
  0.634
ATP5L2
ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] (100 aa)
     
   
  0.593
RIMBP3B
RIMS binding protein 3B (1639 aa)
           
  0.560
CECR6
Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 (578 aa)
           
  0.560
POTEH
POTE ankyrin domain family member H (545 aa)
           
  0.531
BPTF
Nucleosome-remodeling factor subunit BPTF; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors; Belongs to the PBTF family (2920 aa)
     
   
  0.529
GSTT2B
Glutathione S-transferase theta-2B; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity; Soluble glutathione S-transferases (244 aa)
     
   
  0.504
AMDHD1
Probable imidazolonepropionase; Amidohydrolase domain containing 1 (426 aa)
           
  0.491
TST
Thiosulfate sulfurtransferase; Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity (By similarity). Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (297 aa)
     
   
  0.489
RIMBP3
RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family (1639 aa)
           
  0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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