node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMDHD1 | DDTL | ENSP00000266736 | ENSP00000215770 | Probable imidazolonepropionase; Amidohydrolase domain containing 1 | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.491 |
ATP5L2 | CECR6 | ENSP00000421076 | ENSP00000329318 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | 0.571 |
ATP5L2 | DDTL | ENSP00000421076 | ENSP00000215770 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.593 |
ATP5L2 | POTEH | ENSP00000421076 | ENSP00000340610 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | POTE ankyrin domain family member H | 0.537 |
ATP5L2 | RIMBP3 | ENSP00000421076 | ENSP00000483386 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.489 |
ATP5L2 | RIMBP3B | ENSP00000421076 | ENSP00000479326 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | RIMS binding protein 3B | 0.570 |
ATP5L2 | SLC35E4 | ENSP00000421076 | ENSP00000339626 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | Solute carrier family 35 member E4; Putative transporter; Solute carriers | 0.648 |
BPTF | DDTL | ENSP00000307208 | ENSP00000215770 | Nucleosome-remodeling factor subunit BPTF; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors; Belongs to the PBTF family | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.529 |
CECR6 | ATP5L2 | ENSP00000329318 | ENSP00000421076 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | 0.571 |
CECR6 | DDTL | ENSP00000329318 | ENSP00000215770 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | D-dopachrome decarboxylase-like protein; May have lyase activity | 0.560 |
CECR6 | POTEH | ENSP00000329318 | ENSP00000340610 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | POTE ankyrin domain family member H | 0.517 |
CECR6 | RIMBP3 | ENSP00000329318 | ENSP00000483386 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | RIMS-binding protein 3A; Component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development. Important for male fertility; Belongs to the RIMBP family | 0.474 |
CECR6 | RIMBP3B | ENSP00000329318 | ENSP00000479326 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | RIMS binding protein 3B | 0.559 |
CECR6 | SLC35E4 | ENSP00000329318 | ENSP00000339626 | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | Solute carrier family 35 member E4; Putative transporter; Solute carriers | 0.631 |
DDTL | AMDHD1 | ENSP00000215770 | ENSP00000266736 | D-dopachrome decarboxylase-like protein; May have lyase activity | Probable imidazolonepropionase; Amidohydrolase domain containing 1 | 0.491 |
DDTL | ATP5L2 | ENSP00000215770 | ENSP00000421076 | D-dopachrome decarboxylase-like protein; May have lyase activity | ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the ce [...] | 0.593 |
DDTL | BPTF | ENSP00000215770 | ENSP00000307208 | D-dopachrome decarboxylase-like protein; May have lyase activity | Nucleosome-remodeling factor subunit BPTF; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors; Belongs to the PBTF family | 0.529 |
DDTL | CECR6 | ENSP00000215770 | ENSP00000329318 | D-dopachrome decarboxylase-like protein; May have lyase activity | Transmembrane protein 121B; Cat eye syndrome chromosome region, candidate 6 | 0.560 |
DDTL | GSTT2B | ENSP00000215770 | ENSP00000290765 | D-dopachrome decarboxylase-like protein; May have lyase activity | Glutathione S-transferase theta-2B; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity; Soluble glutathione S-transferases | 0.504 |
DDTL | POTEH | ENSP00000215770 | ENSP00000340610 | D-dopachrome decarboxylase-like protein; May have lyase activity | POTE ankyrin domain family member H | 0.531 |