node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC10 | ZNF184 | ENSP00000319412 | ENSP00000211936 | Armadillo repeat-containing protein 10; May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53; Armadillo repeat containing | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.514 |
CAP2 | PPP1R18 | ENSP00000229922 | ENSP00000274853 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family | Phostensin; Isoform 1- May target protein phosphatase 1 to F-actin cytoskeleton | 0.400 |
CAP2 | SF3B5 | ENSP00000229922 | ENSP00000356541 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family | Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA | 0.412 |
CAP2 | ZNF184 | ENSP00000229922 | ENSP00000211936 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.466 |
HMGN4 | POM121L2 | ENSP00000366798 | ENSP00000392726 | High mobility group nucleosomal binding domain 4; Belongs to the HMGN family | POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family | 0.536 |
HMGN4 | ZNF184 | ENSP00000366798 | ENSP00000211936 | High mobility group nucleosomal binding domain 4; Belongs to the HMGN family | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.463 |
MEX3A | ZNF184 | ENSP00000432845 | ENSP00000211936 | RNA-binding protein MEX3A; RNA binding protein, may be involved in post- transcriptional regulatory mechanisms; Ring finger proteins | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.510 |
POM121L2 | HMGN4 | ENSP00000392726 | ENSP00000366798 | POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family | High mobility group nucleosomal binding domain 4; Belongs to the HMGN family | 0.536 |
POM121L2 | PRSS16 | ENSP00000392726 | ENSP00000230582 | POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family | Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family | 0.558 |
POM121L2 | ZNF184 | ENSP00000392726 | ENSP00000211936 | POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.578 |
PPP1R18 | CAP2 | ENSP00000274853 | ENSP00000229922 | Phostensin; Isoform 1- May target protein phosphatase 1 to F-actin cytoskeleton | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family | 0.400 |
PPP1R18 | SF3B5 | ENSP00000274853 | ENSP00000356541 | Phostensin; Isoform 1- May target protein phosphatase 1 to F-actin cytoskeleton | Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA | 0.431 |
PPP1R18 | ZNF184 | ENSP00000274853 | ENSP00000211936 | Phostensin; Isoform 1- May target protein phosphatase 1 to F-actin cytoskeleton | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.545 |
PRSS16 | POM121L2 | ENSP00000230582 | ENSP00000392726 | Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family | POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family | 0.558 |
PRSS16 | ZNF184 | ENSP00000230582 | ENSP00000211936 | Thymus-specific serine protease; Protease that may play a role in T-cell development; Belongs to the peptidase S28 family | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.532 |
RRP8 | ZNF184 | ENSP00000254605 | ENSP00000211936 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell- upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at ’Lys- 9’ (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.542 |
SF3B5 | CAP2 | ENSP00000356541 | ENSP00000229922 | Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family | 0.412 |
SF3B5 | PPP1R18 | ENSP00000356541 | ENSP00000274853 | Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA | Phostensin; Isoform 1- May target protein phosphatase 1 to F-actin cytoskeleton | 0.431 |
SF3B5 | ZNF184 | ENSP00000356541 | ENSP00000211936 | Splicing factor 3B subunit 5; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for ’A’ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.533 |
TRIM28 | ZNF184 | ENSP00000253024 | ENSP00000211936 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 184; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.904 |