HBQ1 protein (human) - STRING database

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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[Homology]

Score

HBQ1

Hemoglobin subunit theta 1 (142 aa)

Predicted Functional Partners:

HBE1

0.952

HBB

0.950

AHSP

0.949

HBA1

0.941

HBZ

0.919

HBG2

0.885

HBD

0.869

ALAS2

0.814

EPB42

0.770

HBA2

0.755

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSP	ALAS2	ENSP00000307199	ENSP00000332369	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	0.920
AHSP	EPB42	ENSP00000307199	ENSP00000300215	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties; Belongs to the transglutaminase superfamily. Transglutaminase family	0.900
AHSP	HBA1	ENSP00000307199	ENSP00000322421	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.987
AHSP	HBA2	ENSP00000307199	ENSP00000251595	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit alpha 2; Involved in oxygen transport from the lung to the various peripheral tissues; Hemoglobin subunits	0.986
AHSP	HBB	ENSP00000307199	ENSP00000333994	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.899
AHSP	HBD	ENSP00000307199	ENSP00000369654	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit delta; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.963
AHSP	HBE1	ENSP00000307199	ENSP00000369586	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit epsilon; The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin; Belongs to the globin family	0.925
AHSP	HBG2	ENSP00000307199	ENSP00000369609	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit gamma-2; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains; Belongs to the globin family	0.791
AHSP	HBQ1	ENSP00000307199	ENSP00000199708	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit theta 1	0.949
AHSP	HBZ	ENSP00000307199	ENSP00000252951	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin	0.823
ALAS2	AHSP	ENSP00000332369	ENSP00000307199	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Alpha-hemoglobin-stabilizing protein; Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia; Belongs to the AHSP family	0.920
ALAS2	EPB42	ENSP00000332369	ENSP00000300215	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties; Belongs to the transglutaminase superfamily. Transglutaminase family	0.918
ALAS2	HBA1	ENSP00000332369	ENSP00000322421	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.657
ALAS2	HBA2	ENSP00000332369	ENSP00000251595	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit alpha 2; Involved in oxygen transport from the lung to the various peripheral tissues; Hemoglobin subunits	0.630
ALAS2	HBB	ENSP00000332369	ENSP00000333994	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.684
ALAS2	HBD	ENSP00000332369	ENSP00000369654	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit delta; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family	0.846
ALAS2	HBE1	ENSP00000332369	ENSP00000369586	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit epsilon; The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin; Belongs to the globin family	0.509
ALAS2	HBG2	ENSP00000332369	ENSP00000369609	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit gamma-2; Gamma chains make up the fetal hemoglobin F, in combination with alpha chains; Belongs to the globin family	0.733
ALAS2	HBQ1	ENSP00000332369	ENSP00000199708	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit theta 1	0.814
ALAS2	HBZ	ENSP00000332369	ENSP00000252951	5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5’-aminolevulinate synthase 2	Hemoglobin subunit zeta; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin	0.532

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