• Version:
  • 11.0 [archived version]
STRINGSTRING
ODF2L ODF2L PRR21 PRR21 FAM47C FAM47C C12orf4 C12orf4 WDR93 WDR93 PCDHB4 PCDHB4 FAM120AOS FAM120AOS CLHC1 CLHC1 NSUN7 NSUN7 ZNF131 ZNF131 MYT1 MYT1
"PCDHB4" - Protocadherin beta-4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDHB4Protocadherin beta-4; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (795 aa)    
Predicted Functional Partners:
FAM47C
Putative protein FAM47C; Family with sequence similarity 47 member C; Belongs to the FAM47 family (1035 aa)
           
  0.560
PRR21
Proline rich 21 (389 aa)
           
  0.542
WDR93
WD repeat-containing protein 93; WD repeat domain containing (686 aa)
           
  0.535
CLHC1
Clathrin heavy chain linker domain containing 1 (586 aa)
           
  0.519
FAM120AOS
Uncharacterized protein FAM120AOS; Family with sequence similarity 120A opposite strand (256 aa)
           
  0.497
MYT1
Myelin transcription factor 1; Binds to the promoter region of genes encoding proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendroglia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up- regulation of myelin gene transcription; Belongs to the MYT1 family (1121 aa)
     
   
  0.495
ZNF131
Zinc finger protein 131; Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling; BTB domain containing (589 aa)
       
 
  0.492
ODF2L
Outer dense fiber of sperm tails 2 like (636 aa)
           
  0.473
C12orf4
Protein C12orf4; Plays a role in mast cell degranulation (552 aa)
           
  0.471
NSUN7
Putative methyltransferase NSUN7; May have S-adenosyl-L-methionine-dependent methyl- transferase activity; NOP2/Sun RNA methyltransferase family (718 aa)
           
  0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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