| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C17orf62 | DHRS7 | ENSP00000388909 | ENSP00000216500 | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | 0.716 |
| C17orf62 | POPDC2 | ENSP00000388909 | ENSP00000264231 | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family | 0.536 |
| C17orf62 | PPAPDC3 | ENSP00000388909 | ENSP00000361338 | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity) | 0.471 |
| C17orf62 | TMEM126A | ENSP00000388909 | ENSP00000306887 | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | Transmembrane protein 126A; Belongs to the TMEM126 family | 0.765 |
| C17orf62 | TMEM38A | ENSP00000388909 | ENSP00000187762 | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores | 0.709 |
| DHRS7 | C17orf62 | ENSP00000216500 | ENSP00000388909 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | 0.716 |
| DHRS7 | POPDC2 | ENSP00000216500 | ENSP00000264231 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family | 0.598 |
| DHRS7 | PPAPDC3 | ENSP00000216500 | ENSP00000361338 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | Inactive phospholipid phosphatase 7; Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity (By similarity) | 0.467 |
| DHRS7 | TMEM126A | ENSP00000216500 | ENSP00000306887 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | Transmembrane protein 126A; Belongs to the TMEM126 family | 0.746 |
| DHRS7 | TMEM38A | ENSP00000216500 | ENSP00000187762 | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores | 0.762 |
| MYL1 | PDLIM7 | ENSP00000307280 | ENSP00000348099 | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity) | 0.925 |
| MYL1 | SRL | ENSP00000307280 | ENSP00000382518 | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Sarcalumenin; May be involved in the regulation of calcium transport | 0.923 |
| MYL1 | TMEM38A | ENSP00000307280 | ENSP00000187762 | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores | 0.833 |
| MYL1 | TNNC2 | ENSP00000307280 | ENSP00000361636 | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components- Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments; EF-hand domain containing | 0.993 |
| PDLIM7 | MYL1 | ENSP00000348099 | ENSP00000307280 | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity) | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.925 |
| PDLIM7 | SRL | ENSP00000348099 | ENSP00000382518 | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity) | Sarcalumenin; May be involved in the regulation of calcium transport | 0.841 |
| PDLIM7 | TMEM38A | ENSP00000348099 | ENSP00000187762 | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity) | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores | 0.834 |
| PDLIM7 | TNNC2 | ENSP00000348099 | ENSP00000361636 | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity) | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components- Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments; EF-hand domain containing | 0.930 |
| POPDC2 | C17orf62 | ENSP00000264231 | ENSP00000388909 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family | Uncharacterized protein C17orf62; Chromosome 17 open reading frame 62 | 0.536 |
| POPDC2 | DHRS7 | ENSP00000264231 | ENSP00000216500 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family | Dehydrogenase/reductase SDR family member 7; Short chain dehydrogenase/reductase superfamily | 0.598 |
