• Version:
  • 11.0 [archived version]
STRINGSTRING
KRT75 KRT75 KRT8 KRT8 KRT7 KRT7 KRT4 KRT4 KRT20 KRT20 KRT3 KRT3 KRT24 KRT24 KRT80 KRT80 KRT5 KRT5 KRT72 KRT72 KRT78 KRT78
"KRT20" - Keratin, type I cytoskeletal 20 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT20Keratin, type I cytoskeletal 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity); Keratins, type I (424 aa)    
Predicted Functional Partners:
KRT7
Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7); Keratins, type II (469 aa)
     
0.939
KRT8
Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle; Keratins, type II (511 aa)
     
0.938
KRT72
Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) (511 aa)
     
0.938
KRT80
Keratin, type II cytoskeletal 80; Keratins, type II (452 aa)
     
0.935
KRT5
Keratin, type II cytoskeletal 5; Keratins, type II (590 aa)
     
0.934
KRT3
Keratin, type II cytoskeletal 3; Keratins, type II (628 aa)
     
0.933
KRT4
Keratin, type II cytoskeletal 4; Keratins, type II; Belongs to the intermediate filament family (520 aa)
     
0.928
KRT75
Keratin, type II cytoskeletal 75; Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle (551 aa)
     
0.926
KRT24
Keratin, type I cytoskeletal 24; Keratins, type I (525 aa)
     
0.925
KRT78
Keratin, type II cytoskeletal 78; Keratins, type II (520 aa)
     
0.924
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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