• Version:
  • 11.0 [archived version]
STRINGSTRING
DPT DPT C11orf1 C11orf1 CASKIN2 CASKIN2 SLC25A42 SLC25A42 KIAA0195 KIAA0195 MANEAL MANEAL TMEM161A TMEM161A CHST7 CHST7 TMEM38A TMEM38A KLHL31 KLHL31 POPDC2 POPDC2
"TMEM161A" - Transmembrane protein 161A in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TMEM161ATransmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis; Belongs to the TMEM161 family (479 aa)    
Predicted Functional Partners:
SLC25A42
Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate; Solute carriers (318 aa)
     
   
  0.794
CASKIN2
Caskin-2; Sterile alpha motif domain containing (1202 aa)
     
   
  0.777
KIAA0195
Transmembrane protein 94; KIAA0195 (1356 aa)
           
  0.775
C11orf1
UPF0686 protein C11orf1; Chromosome 11 open reading frame 1; Belongs to the UPF0686 family (150 aa)
           
  0.700
POPDC2
Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density; Belongs to the popeye family (364 aa)
           
  0.659
MANEAL
Glycoprotein endo-alpha-1,2-mannosidase-like protein; Mannosidase endo-alpha like; Belongs to the glycosyl hydrolase 99 family (457 aa)
           
  0.597
KLHL31
Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE); BTB domain containing (634 aa)
     
   
  0.551
DPT
Dermatopontin; Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity); Belongs to the dermatopontin family (201 aa)
           
  0.512
TMEM38A
Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (299 aa)
     
   
  0.510
CHST7
Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1- [...] (486 aa)
           
  0.497
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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