node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACSM3 | FAM136A | ENSP00000289416 | ENSP00000037869 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid-CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity); Acyl-CoA synthetase family | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.725 |
COLGALT1 | FAM136A | ENSP00000252599 | ENSP00000037869 | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.514 |
COLGALT1 | HINT2 | ENSP00000252599 | ENSP00000259667 | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity; Belongs to the HINT family | 0.471 |
COLGALT1 | NAA38 | ENSP00000252599 | ENSP00000332103 | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | N-alpha-acetyltransferase 38, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues; LSm proteins | 0.495 |
COLGALT1 | PRR12 | ENSP00000252599 | ENSP00000394510 | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | Proline-rich protein 12; Proline rich 12 | 0.502 |
CUTA | FAM136A | ENSP00000363624 | ENSP00000037869 | Protein CutA; May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE); Belongs to the CutA family | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.550 |
DAP3 | FAM136A | ENSP00000357320 | ENSP00000037869 | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.532 |
DTNA | FAM136A | ENSP00000470152 | ENSP00000037869 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.665 |
EXOSC5 | FAM136A | ENSP00000221233 | ENSP00000037869 | Exosome complex component RRP46; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 0.661 |
FAM136A | ACSM3 | ENSP00000037869 | ENSP00000289416 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Has medium-chain fatty acid-CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity); Acyl-CoA synthetase family | 0.725 |
FAM136A | COLGALT1 | ENSP00000037869 | ENSP00000252599 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | 0.514 |
FAM136A | CUTA | ENSP00000037869 | ENSP00000363624 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Protein CutA; May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE); Belongs to the CutA family | 0.550 |
FAM136A | DAP3 | ENSP00000037869 | ENSP00000357320 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | 28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family | 0.532 |
FAM136A | DTNA | ENSP00000037869 | ENSP00000470152 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.665 |
FAM136A | EXOSC5 | ENSP00000037869 | ENSP00000221233 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Exosome complex component RRP46; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...] | 0.661 |
FAM136A | HINT2 | ENSP00000037869 | ENSP00000259667 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity; Belongs to the HINT family | 0.512 |
FAM136A | NAA38 | ENSP00000037869 | ENSP00000332103 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | N-alpha-acetyltransferase 38, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues; LSm proteins | 0.553 |
FAM136A | PRMT5 | ENSP00000037869 | ENSP00000319169 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H and may regulate its transcriptional elongation properties. Mono- and dimethylates arginine residues of myelin b [...] | 0.656 |
FAM136A | PRR12 | ENSP00000037869 | ENSP00000394510 | Protein FAM136A; Family with sequence similarity 136 member A; Belongs to the FAM136 family | Proline-rich protein 12; Proline rich 12 | 0.521 |
HINT2 | COLGALT1 | ENSP00000259667 | ENSP00000252599 | Histidine triad nucleotide-binding protein 2, mitochondrial; Hydrolase probably involved in steroid biosynthesis. May play a role in apoptosis. Has adenosine phosphoramidase activity; Belongs to the HINT family | Procollagen galactosyltransferase 1; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix; Belongs to the glycosyltransferase 25 family | 0.471 |