TSR3 protein (human) - STRING database

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TSR3

Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis (312 aa)

Predicted Functional Partners:

TSR2

0.835

TSR1

0.804

TBL2

0.729

OPLAH

0.723

NOB1

0.722

WBSCR22

0.717

LTV1

0.708

CFP

0.663

B3GALTL

0.647

PDCD2

0.641

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GALTL	CFP	ENSP00000343002	ENSP00000247153	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	0.959
B3GALTL	TSR1	ENSP00000343002	ENSP00000301364	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus	0.405
B3GALTL	TSR3	ENSP00000343002	ENSP00000007390	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.647
CFP	B3GALTL	ENSP00000247153	ENSP00000343002	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	Beta-1,3-glucosyltransferase; O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan	0.959
CFP	TSR1	ENSP00000247153	ENSP00000301364	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus	0.491
CFP	TSR2	ENSP00000247153	ENSP00000364293	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing	0.446
CFP	TSR3	ENSP00000247153	ENSP00000007390	Properdin; A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.663
LTV1	NOB1	ENSP00000356548	ENSP00000268802	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	0.999
LTV1	TSR1	ENSP00000356548	ENSP00000301364	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus	0.999
LTV1	TSR2	ENSP00000356548	ENSP00000364293	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing	0.882
LTV1	TSR3	ENSP00000356548	ENSP00000007390	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.708
LTV1	WBSCR22	ENSP00000356548	ENSP00000401191	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	Probable 18S rRNA (guanine-N(7))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivat [...]	0.998
NOB1	LTV1	ENSP00000268802	ENSP00000356548	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	Protein LTV1 homolog; LTV1 ribosome biogenesis factor	0.999
NOB1	TSR1	ENSP00000268802	ENSP00000301364	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus	0.999
NOB1	TSR2	ENSP00000268802	ENSP00000364293	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	Pre-rRNA-processing protein TSR2 homolog; May be involved in 20S pre-rRNA processing	0.839
NOB1	TSR3	ENSP00000268802	ENSP00000007390	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.722
NOB1	WBSCR22	ENSP00000268802	ENSP00000401191	RNA-binding protein NOB1; May play a role in mRNA degradation; Belongs to the NOB1 family	Probable 18S rRNA (guanine-N(7))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivat [...]	0.985
OPLAH	TSR3	ENSP00000480476	ENSP00000007390	5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.723
PDCD2	TSR3	ENSP00000439467	ENSP00000007390	Programmed cell death protein 2; May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation; Zinc fingers MYND-type	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.641
TBL2	TSR3	ENSP00000307260	ENSP00000007390	Transducin beta-like protein 2; WD repeat domain containing	Ribosome biogenesis protein TSR3 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis	0.729

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