• Version:
  • 11.0 [archived version]
STRINGSTRING
GCFC2 GCFC2 ZNHIT3 ZNHIT3 ZBTB11 ZBTB11 PCDHGA3 PCDHGA3 ZZEF1 ZZEF1 FBXL17 FBXL17 WDR54 WDR54 CCDC140 CCDC140 DUS3L DUS3L OSCP1 OSCP1 SPCS2 SPCS2
"WDR54" - WD repeat-containing protein 54 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR54WD repeat-containing protein 54; WD repeat domain containing (334 aa)    
Predicted Functional Partners:
OSCP1
Protein OSCP1; May be involved in drug clearance in the placenta (379 aa)
       
      0.768
ZZEF1
Zinc finger ZZ-type and EF-hand domain containing 1 (2961 aa)
           
  0.733
FBXL17
F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (701 aa)
           
  0.704
CCDC140
Coiled-coil domain containing 140 (163 aa)
           
  0.647
ZBTB11
Zinc finger and BTB domain-containing protein 11; May be involved in transcriptional regulation; BTB domain containing (1053 aa)
           
  0.620
DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (650 aa)
           
  0.609
ZNHIT3
Zinc finger HIT-type containing 3 (155 aa)
           
  0.598
SPCS2
Signal peptidase complex subunit 2; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (226 aa)
           
  0.590
PCDHGA3
Protocadherin gamma-A3; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (932 aa)
           
  0.562
GCFC2
GC-rich sequence DNA-binding factor 2; Factor that represses transcription. It binds to the GC- rich sequences (5’-GCGGGGC-3’) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons; Belongs to the GCF family (781 aa)
           
  0.553
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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