26 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MRPS10	Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family (201 aa)
	MRPS35	Mitochondrial ribosomal protein S35 (323 aa)
	MRPL32	Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family (188 aa)
	MRPL27	Mitochondrial ribosomal protein L27 (148 aa)
	MRPL34	Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
	MRPL4	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
	MRPL44	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins (332 aa)
	MRPS9	Mitochondrial ribosomal protein S9 (396 aa)
	MRPL15	Mitochondrial ribosomal protein L15 (296 aa)
	MRPL3	Mitochondrial ribosomal protein L3 (348 aa)
	MRPS5	Mitochondrial ribosomal protein S5 (430 aa)
	MRPL49	Mitochondrial ribosomal protein L49 (166 aa)
	MRPL17	Mitochondrial ribosomal protein L17 (175 aa)
	MRPL33	Mitochondrial ribosomal protein L33 (65 aa)
	MRPL16	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family (251 aa)
	MRPL13	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family (178 aa)
	MRPL46	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family (279 aa)
	MRPL40	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family (206 aa)
	MRPL43	Mitochondrial ribosomal protein L43 (235 aa)
	HIBCH	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
	DAP3	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family (398 aa)
	MRPL41	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (137 aa)
	MRPS2	Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (296 aa)
	MRPL19	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family (292 aa)
	MRPL47	Mitochondrial ribosomal protein L47 (250 aa)
	ENSG00000276345	Mitochondrial ribosomal protein L23 (153 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAP3	ENSG00000276345	ENSP00000357320	ENSP00000478035	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L23	0.775
DAP3	HIBCH	ENSP00000357320	ENSP00000352706	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA	0.804
DAP3	MRPL13	ENSP00000357320	ENSP00000306548	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.997
DAP3	MRPL15	ENSP00000357320	ENSP00000260102	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L15	0.997
DAP3	MRPL16	ENSP00000357320	ENSP00000300151	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family	0.996
DAP3	MRPL17	ENSP00000357320	ENSP00000288937	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L17	0.999
DAP3	MRPL19	ENSP00000357320	ENSP00000377486	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.998
DAP3	MRPL27	ENSP00000357320	ENSP00000225969	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L27	0.996
DAP3	MRPL3	ENSP00000357320	ENSP00000264995	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L3	0.998
DAP3	MRPL32	ENSP00000357320	ENSP00000223324	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family	0.995
DAP3	MRPL33	ENSP00000357320	ENSP00000296102	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L33	0.992
DAP3	MRPL34	ENSP00000357320	ENSP00000252602	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family	0.991
DAP3	MRPL4	ENSP00000357320	ENSP00000253099	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family	0.999
DAP3	MRPL40	ENSP00000357320	ENSP00000333401	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family	0.997
DAP3	MRPL41	ENSP00000357320	ENSP00000360498	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins	0.996
DAP3	MRPL43	ENSP00000357320	ENSP00000339844	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L43	0.997
DAP3	MRPL44	ENSP00000357320	ENSP00000258383	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Mitochondrial ribosomal proteins	0.998
DAP3	MRPL46	ENSP00000357320	ENSP00000312311	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family	0.999
DAP3	MRPL47	ENSP00000357320	ENSP00000417602	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L47	0.997
DAP3	MRPL49	ENSP00000357320	ENSP00000279242	28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family	Mitochondrial ribosomal protein L49	0.997

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