• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF165 ZNF165 ZNF263 ZNF263 ZNF18 ZNF18 SIN3A SIN3A ZNF483 ZNF483 ZNF397 ZNF397 SIN3B SIN3B ZNF446 ZNF446 ZNF444 ZNF444 WDR59 WDR59 ZSCAN30 ZSCAN30 ZSCAN16 ZSCAN16 ZNF24 ZNF24 ZKSCAN4 ZKSCAN4 ZSCAN32 ZSCAN32 ZNF232 ZNF232 DCAF10 DCAF10 ZSCAN18 ZSCAN18 ZSCAN22 ZSCAN22 ZNF496 ZNF496 PGBD1 PGBD1 ZNF396 ZNF396 ZSCAN9 ZSCAN9 ZSCAN21 ZSCAN21 ZSCAN23 ZSCAN23 ZKSCAN7 ZKSCAN7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZNF263Zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family (683 aa)
ZNF232Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing (444 aa)
PGBD1PiggyBac transposable element-derived protein 1; Scavenger receptor cysteine rich domain containing; DNA transposon derived genes (809 aa)
ZNF24Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family (368 aa)
WDR59GATOR complex protein WDR59; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1; Belongs to the WD repeat WDR59 family (974 aa)
ZKSCAN7Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (754 aa)
ZSCAN23Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation; SCAN domain containing (389 aa)
ZSCAN21Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing (473 aa)
ZNF496Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family (587 aa)
ZNF396Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors; Belongs to the krueppel C2H2-type zinc-finger protein family (333 aa)
ZNF483Zinc finger protein 483; May be involved in transcriptional regulation; SCAN domain containing (744 aa)
ZNF18Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (549 aa)
ZNF397Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing (534 aa)
ZSCAN22Zinc finger and SCAN domain-containing protein 22; May be involved in transcriptional regulation; SCAN domain containing (491 aa)
ZNF444Zinc finger protein 444; Transcriptional regulator. Binds to the 5’-flanking critical region of the SCARF1 promoter; Belongs to the krueppel C2H2-type zinc-finger protein family (327 aa)
ZKSCAN4Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family (545 aa)
ZSCAN16Zinc finger and SCAN domain-containing protein 16; May be involved in transcriptional regulation; SCAN domain containing (348 aa)
ZNF165Zinc finger protein 165; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (485 aa)
DCAF10DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; DDB1 and CUL4 associated factors (559 aa)
SIN3BPaired amphipathic helix protein Sin3b; Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression (1162 aa)
SIN3APaired amphipathic helix protein Sin3a; Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates wit [...] (1273 aa)
ZSCAN32Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (697 aa)
ZSCAN30Zinc finger and SCAN domain-containing protein 30; May be involved in transcriptional regulation; SCAN domain containing (494 aa)
ZSCAN9Zinc finger and SCAN domain containing 9 (445 aa)
ZSCAN18Zinc finger and SCAN domain-containing protein 18; May be involved in transcriptional regulation; SCAN domain containing (566 aa)
ZNF446Zinc finger protein 446; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (450 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >