• Version:
  • 11.0 [archived version]
STRINGSTRING
ABCE1 ABCE1 GNB2L1 GNB2L1 ENSG00000270800 ENSG00000270800 RPL15 RPL15 RPS27 RPS27 RPS16 RPS16 SRP14 SRP14 ENSG00000215472 ENSG00000215472 RPS23 RPS23 RPL38 RPL38 SRP54 SRP54 RPS9 RPS9 RPS15A RPS15A SEC61B SEC61B RPL39 RPL39 RPS7 RPS7 ETF1 ETF1 RPL30 RPL30 SEC61G SEC61G RPL37 RPL37 RPL34 RPL34 RPS17 RPS17 RPS11 RPS11 RPL27 RPL27 RPL36 RPL36 RPN1 RPN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SEC61-beta family (96 aa)
RPS16Ribosomal protein S16 (146 aa)
SRP14Signal recognition particle 14 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding (136 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
RPL3760S ribosomal protein L37; Binds to the 23S rRNA; L ribosomal proteins (97 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains; Belongs to the OST1 family (607 aa)
ABCE1ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5’-phosphorylated 2’,5’-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly; Belongs to the ABC transporter superfamily. ABCE family (599 aa)
RPS2340S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
RPS9Ribosomal protein S9 (194 aa)
RPL15Ribosomal protein L15 (204 aa)
RPL38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family (70 aa)
RPS15ARibosomal protein S15a; Belongs to the universal ribosomal protein uS8 family (130 aa)
RPS740S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family (194 aa)
RPS17Ribosomal protein S17 (135 aa)
ETF1Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (437 aa)
RPL39Ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family (51 aa)
RPS2740S ribosomal protein S27; Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs; Belongs to the eukaryotic ribosomal protein eS27 family (84 aa)
RPL3460S ribosomal protein L34; Component of the large ribosomal subunit (117 aa)
SEC61GProtein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SecE/SEC61-gamma family (68 aa)
GNB2L1Receptor of activated protein C kinase 1; (Microbial infection) Contributes to the cap-independent internal ribosome entry site (IRES)-mediated translation by some RNA viruses; Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily (317 aa)
RPL30Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family (115 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein) (504 aa)
ENSG00000215472RPL17-C18orf32 readthrough; Belongs to the universal ribosomal protein uL22 family (228 aa)
RPL3660S ribosomal protein L36; Component of the large ribosomal subunit (105 aa)
RPL2760S ribosomal protein L27; Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (136 aa)
ENSG00000270800RPS10-NUDT3 readthrough (286 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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