• Version:
  • 11.0 [archived version]
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RPL8 RPL8 RPL27 RPL27 RPL39 RPL39 RPL12 RPL12 RPL38 RPL38 RPL17 RPL17 RPL7A RPL7A RPL23A RPL23A SEC61A1 SEC61A1 RPL22 RPL22 RPL30 RPL30 RPL11 RPL11 RPL23 RPL23 SEC61B SEC61B RPL24 RPL24 RPL15 RPL15 RPL32 RPL32 RPN1 RPN1 RPL37A RPL37A RPL34 RPL34 ENSG00000215472 ENSG00000215472 RPL36A RPL36A SEC61G SEC61G RPL26 RPL26 RPL37 RPL37 OST4 OST4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SEC61-beta family (96 aa)
SEC61A1Protein transport protein Sec61 subunit alpha isoform 1; Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins. Plays a role in pronephric kidney tubule development (By similarity); Belongs to the SecY/SEC61-alpha family (476 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
RPL3760S ribosomal protein L37; Binds to the 23S rRNA; L ribosomal proteins (97 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains; Belongs to the OST1 family (607 aa)
RPL15Ribosomal protein L15 (204 aa)
RPL38Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family (70 aa)
RPL22Ribosomal protein L22; Belongs to the eukaryotic ribosomal protein eL22 family (128 aa)
RPL1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA (165 aa)
RPL39Ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family (51 aa)
RPL7ARibosomal protein L7a (266 aa)
RPL1160S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] (178 aa)
RPL24Ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family (157 aa)
RPL3460S ribosomal protein L34; Component of the large ribosomal subunit (117 aa)
SEC61GProtein transport protein Sec61 subunit gamma; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SecE/SEC61-gamma family (68 aa)
RPL23A60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family (156 aa)
RPL1760S ribosomal protein L17; Component of the large ribosomal subunit; Belongs to the universal ribosomal protein uL22 family (184 aa)
RPL36ARibosomal protein L36a (142 aa)
RPL32Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family (135 aa)
RPL37ARibosomal protein L37a (92 aa)
RPL23Ribosomal protein L23 (140 aa)
RPL30Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family (115 aa)
OST4Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4; Acts as component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for efficient N- glycosylation. Specifically involved in maintaining stability of STT3A-containing OST complexes; Belongs to the OST4 family (37 aa)
ENSG00000215472RPL17-C18orf32 readthrough; Belongs to the universal ribosomal protein uL22 family (228 aa)
RPL26Ribosomal protein L26 (145 aa)
RPL2760S ribosomal protein L27; Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (136 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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