• Version:
  • 11.0 [archived version]
STRINGSTRING
OBP2A OBP2A TXNDC15 TXNDC15 LRP2 LRP2 OBP2B OBP2B COL6A2 COL6A2 ERBB2IP ERBB2IP OR1G1 OR1G1 CLN5 CLN5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRP2Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hyp [...] (4655 aa)
COL6A2Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein; Collagens (1019 aa)
OR1G1Olfactory receptor 1G1; Odorant receptor; Olfactory receptors, family 1 (313 aa)
TXNDC15Thioredoxin domain containing 15 (360 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5; Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (407 aa)
ERBB2IPErbin; Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ’Tyr-1248’ of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion; Belongs to the LAP (LRR and PDZ) protein family (1419 aa)
OBP2AOdorant-binding protein 2a; Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids; Lipocalins (170 aa)
OBP2BOdorant-binding protein 2b; Probably binds and transports small hydrophobic volatile molecules; Belongs to the calycin superfamily. Lipocalin family (170 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]