• Version:
  • 11.0 [archived version]
STRINGSTRING
ALKBH8 ALKBH8 RPS5 RPS5 RPS23 RPS23 LTV1 LTV1 RPS7 RPS7 TRMT112 TRMT112 RPS27 RPS27 N6AMT1 N6AMT1 RPS17 RPS17 RPS3A RPS3A RPS18 RPS18 RPS11 RPS11 RPS16 RPS16 WBSCR22 WBSCR22 RPS13 RPS13 RPS4X RPS4X RPS6 RPS6 RPS9 RPS9 RPS15A RPS15A RPS8 RPS8 RPS25 RPS25 RPS15 RPS15 RPS19 RPS19 TSR1 TSR1 RPS28 RPS28 RPS14 RPS14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS16Ribosomal protein S16 (146 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family (158 aa)
RPS2340S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa)
TSR1Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus (804 aa)
RPS9Ribosomal protein S9 (194 aa)
N6AMT1HemK methyltransferase family member 2; Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid; Belongs to the eukaryotic/archaeal PrmC-related family (214 aa)
RPS15ARibosomal protein S15a; Belongs to the universal ribosomal protein uS8 family (130 aa)
RPS740S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family (194 aa)
RPS17Ribosomal protein S17 (135 aa)
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3; Belongs to the eukaryotic ribosomal protein eS1 family (264 aa)
LTV1Protein LTV1 homolog; LTV1 ribosome biogenesis factor (475 aa)
RPS2740S ribosomal protein S27; Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs; Belongs to the eukaryotic ribosomal protein eS27 family (84 aa)
RPS4XRibosomal protein S4, X-linked; Belongs to the eukaryotic ribosomal protein eS4 family (263 aa)
RPS640S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins (249 aa)
RPS8Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family (208 aa)
RPS14Ribosomal protein S14 (151 aa)
RPS1840S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; S ribosomal proteins (152 aa)
ALKBH8Alkylated DNA repair protein alkB homolog 8; Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in t [...] (667 aa)
WBSCR22Probable 18S rRNA (guanine-N(7))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivat [...] (298 aa)
RPS25Ribosomal protein S25 (125 aa)
RPS13Ribosomal protein S13 (151 aa)
TRMT112Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on ’Gln-185’, using S-adenosyl L- methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5- methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading t [...] (125 aa)
RPS15Ribosomal protein S15 (145 aa)
RPS1940S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family (145 aa)
RPS28Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family (69 aa)
RPS5Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family (204 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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