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  • 11.0 [archived version]
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MRPL28 MRPL28 GFM1 GFM1 MRPS36 MRPS36 ERAL1 ERAL1 MRPS25 MRPS25 MRPL39 MRPL39 MRPL53 MRPL53 PTCD3 PTCD3 MRPS18C MRPS18C MRPS34 MRPS34 MRPS31 MRPS31 MRPS35 MRPS35 MRPL46 MRPL46 MRPS18B MRPS18B MRPL34 MRPL34 MRPS28 MRPS28 MRPS7 MRPS7 MRPL48 MRPL48 MRPL49 MRPL49 MRPL57 MRPL57 MRPS24 MRPS24 MRPL38 MRPL38 MRPS23 MRPS23 MRPL51 MRPL51 GADD45GIP1 GADD45GIP1 MRPL10 MRPL10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MRPS35Mitochondrial ribosomal protein S35 (323 aa)
MRPS3428S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation (225 aa)
MRPL28Mitochondrial ribosomal protein L28 (256 aa)
MRPL51Mitochondrial ribosomal protein L51; Belongs to the mitochondrion-specific ribosomal protein mL51 family (128 aa)
MRPS7Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family (242 aa)
MRPL34Mitochondrial ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family (92 aa)
MRPS25Mitochondrial ribosomal protein S25 (173 aa)
PTCD3Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation (689 aa)
ERAL1GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3’ terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (437 aa)
MRPS36Mitochondrial ribosomal protein S36 (103 aa)
MRPL53Mitochondrial ribosomal protein L53 (112 aa)
MRPS18BMitochondrial ribosomal protein S18B; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily (258 aa)
MRPS28Mitochondrial ribosomal protein S28; Belongs to the bacterial ribosomal protein bS1 family (187 aa)
MRPL49Mitochondrial ribosomal protein L49 (166 aa)
MRPL10Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family (271 aa)
MRPS18CMitochondrial ribosomal protein S18C (142 aa)
MRPL39Mitochondrial ribosomal protein L39; Belongs to the mitochondrion-specific ribosomal protein mL39 family (353 aa)
MRPL38Mitochondrial ribosomal protein L38; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily (380 aa)
MRPL48Mitochondrial ribosomal protein L48 (212 aa)
MRPL57Mitochondrial ribosomal protein L57; Belongs to the mitochondrion-specific ribosomal protein mL63 family (102 aa)
MRPL46Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family (279 aa)
MRPS31Mitochondrial ribosomal protein S31 (395 aa)
MRPS24Mitochondrial ribosomal protein S24; Belongs to the universal ribosomal protein uS3 family (167 aa)
MRPS23Mitochondrial ribosomal protein S23; Belongs to the mitochondrion-specific ribosomal protein mS23 family (190 aa)
GADD45GIP1Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis (222 aa)
GFM1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mit [...] (751 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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