• Version:
  • 11.0 [archived version]
STRINGSTRING
CLIC1 CLIC1 CLIC2 CLIC2 ENO1 ENO1 ENSG00000280433 ENSG00000280433 TRAPPC3L TRAPPC3L TRAPPC6A TRAPPC6A TRAPPC6B TRAPPC6B TRAPPC8 TRAPPC8 TRAPPC2 TRAPPC2 TRAPPC12 TRAPPC12 GLB1 GLB1 TRAPPC4 TRAPPC4 TRAPPC11 TRAPPC11 TRAPPC3 TRAPPC3 TRAPPC1 TRAPPC1 BCL2L14 BCL2L14 TRAPPC2L TRAPPC2L TRAPPC13 TRAPPC13 TRAPPC5 TRAPPC5 TRAPPC9 TRAPPC9 TRAPPC10 TRAPPC10 C7orf43 C7orf43 STMN4 STMN4 TBC1D14 TBC1D14 KANK4 KANK4 CABS1 CABS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAPPC6ATrafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes; Trafficking protein particle complex (173 aa)
ENO1Alpha-enolase; Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production; Belongs to the enolase family (434 aa)
CABS1Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1 (395 aa)
TRAPPC8Trafficking protein particle complex subunit 8; May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Trafficking protein particle complex (1435 aa)
TRAPPC10Trafficking protein particle complex subunit 10; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TMEM1 family (1259 aa)
TRAPPC2LTrafficking protein particle complex subunit 2-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. Sedlin subfamily (140 aa)
TRAPPC1Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily (145 aa)
GLB1Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans; Belongs to the glycosyl hydrolase 35 family (677 aa)
BCL2L14Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family (327 aa)
TRAPPC12Trafficking protein particle complex subunit 12; Plays an important role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores. May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Tetratricopeptide repeat domain containing (735 aa)
C7orf43Uncharacterized protein C7orf43; Chromosome 7 open reading frame 43 (580 aa)
TRAPPC6BTrafficking protein particle complex subunit 6B; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (158 aa)
TRAPPC11Trafficking protein particle complex subunit 11; Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Trafficking protein particle complex (1133 aa)
STMN4Stathmin-4; Stathmin 4; Stathmins (216 aa)
TRAPPC3LTrafficking protein particle complex subunit 3-like protein; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (181 aa)
CLIC2Chloride intracellular channel protein 2; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx (247 aa)
KANK4KN motif and ankyrin repeat domain-containing protein 4; May be involved in the control of cytoskeleton formation by regulating actin polymerization; Ankyrin repeat domain containing (995 aa)
CLIC1Chloride intracellular channel protein 1; Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle (241 aa)
TRAPPC9Trafficking protein particle complex subunit 9; Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the NIBP family (1246 aa)
TBC1D14TBC1 domain family member 14; Negative regulator of starvation-induced autophagosome formation (693 aa)
TRAPPC2Trafficking protein particle complex subunit 2; Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. Sedlin subfamily (174 aa)
TRAPPC13Trafficking protein particle complex 13 (418 aa)
TRAPPC4Trafficking protein particle complex subunit 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (219 aa)
TRAPPC5Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (188 aa)
TRAPPC3Trafficking protein particle complex subunit 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Trafficking protein particle complex (188 aa)
ENSG00000280433TMEM1 protein (203 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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