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  • 11.0 [archived version]
STRINGSTRING
KRTAP1-1 KRTAP1-1 KRTAP9-2 KRTAP9-2 NUFIP2 NUFIP2 KRTAP11-1 KRTAP11-1 RGS17 RGS17 KRTAP5-4 KRTAP5-4 CRCT1 CRCT1 KRTAP10-8 KRTAP10-8 LCE1B LCE1B LCE4A LCE4A KRTAP9-3 KRTAP9-3 LCE3A LCE3A LCE2C LCE2C KRTAP5-9 KRTAP5-9 KRTAP5-2 KRTAP5-2 LCE3B LCE3B LCE5A LCE5A LCE1D LCE1D LCE1E LCE1E LCE1C LCE1C LCE1F LCE1F CRY2 CRY2 LCE3C LCE3C SMCP SMCP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUFIP2Nuclear fragile X mental retardation-interacting protein 2; Binds RNA (695 aa)
KRTAP1-1Keratin-associated protein 1-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 1 family (177 aa)
LCE1DLate cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum (114 aa)
KRTAP11-1Keratin-associated protein 11-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (163 aa)
LCE5ALate cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (118 aa)
LCE1FLate cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum (118 aa)
LCE3CLate cornified envelope protein 3C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (94 aa)
LCE3ALate cornified envelope protein 3A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (89 aa)
LCE3BLate cornified envelope protein 3B; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (95 aa)
KRTAP10-8Keratin-associated protein 10-8; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 10 family (259 aa)
LCE1BLate cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum (118 aa)
RGS17Regulator of G-protein signaling 17; Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity) (210 aa)
SMCPSperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity) (116 aa)
LCE1ELate cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum (118 aa)
LCE4ALate cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family (99 aa)
LCE2CLate cornified envelope protein 2C; Precursors of the cornified envelope of the stratum (110 aa)
CRCT1Cysteine rich C-terminal 1 (99 aa)
KRTAP9-2Keratin-associated protein 9-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (174 aa)
KRTAP5-4Keratin associated protein 5-4 (228 aa)
KRTAP9-3Keratin-associated protein 9-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (159 aa)
KRTAP5-2Keratin-associated protein 5-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 5 family (177 aa)
KRTAP5-9Keratin-associated protein 5-9; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins (169 aa)
LCE1CLate cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum (118 aa)
CRY2Cryptochrome-2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots ’circa’ (about) and ’diem’ (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and rena [...] (614 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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