|
Your Input:
|
||||
| TLX2 | T-cell leukemia homeobox protein 2; Transcription activator that binds DNA elements with the consensus sequence 5’-CGGTAATTGG-3’. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity); NKL subclass homeoboxes and pseudogenes (284 aa) | |||
| BARX1 | Homeobox protein BarH-like 1; Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter; NKL subclass homeoboxes and pseudogenes (254 aa) | |||
| BARHL1 | BarH-like 1 homeobox protein; NKL subclass homeoboxes and pseudogenes (327 aa) | |||
| BARX2 | Homeobox protein BarH-like 2; Transcription factor. Binds optimally to the DNA consensus sequence 5’-YYTAATGRTTTTY-3’. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia (By similarity); Belongs to the BAR homeobox family (279 aa) | |||
| WNT4 | Protein Wnt-4; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue; Endogenous ligands (351 aa) | |||
| TLX3 | T-cell leukemia homeobox protein 3; NKL subclass homeoboxes and pseudogenes (291 aa) | |||
| NPM1 | Nucleophosmin; Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double- stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. [...] (294 aa) | |||
| TMEM107 | Transmembrane protein 107; Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins (146 aa) | |||
| CXCR2 | C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (360 aa) | |||
| DBX2 | Homeobox protein DBX2; NKL subclass homeoboxes and pseudogenes (339 aa) | |||
| HLX | H2.0-like homeobox protein; Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity); Belongs to the H2.0 homeobox family (488 aa) | |||
| VENTX | Homeobox protein VENTX; May be involved in ventralization; NKL subclass homeoboxes and pseudogenes (258 aa) | |||
| LBX1 | Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes (281 aa) | |||
| TLX1 | T-cell leukemia homeobox protein 1; Controls the genesis of the spleen. Binds to the DNA sequence 5’-GGCGGTAAGTGG-3’; NKL subclass homeoboxes and pseudogenes (330 aa) | |||
| BARHL2 | BarH-like 2 homeobox protein; Potential regulator of neural basic helix-loop-helix genes; NKL subclass homeoboxes and pseudogenes (387 aa) | |||
| LBX2 | Transcription factor LBX2; Putative transcription factor; NKL subclass homeoboxes and pseudogenes (198 aa) | |||
| TMEM80 | Transmembrane protein 80 (216 aa) | |||
| NKX1-1 | NK1 transcription factor-related protein 1; NKL subclass homeoboxes and pseudogenes; Belongs to the NK-1 homeobox family (411 aa) | |||
| DBX1 | Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity); NKL subclass homeoboxes and pseudogenes (343 aa) | |||
| NKX1-2 | NK1 transcription factor-related protein 2; May function in cell specification, particularly in the CNS; NKL subclass homeoboxes and pseudogenes (310 aa) | |||
