• Version:
  • 11.0 [archived version]
STRINGSTRING
TRUB1 TRUB1 DKC1 DKC1 SULT4A1 SULT4A1 ERMN ERMN MRPL2 MRPL2 RPL8 RPL8 RPL34 RPL34 RPL23A RPL23A RPL37 RPL37 RPL35A RPL35A RPL9 RPL9 RPL30 RPL30 RPL23 RPL23 RPL27 RPL27 RPL22 RPL22 RPL26 RPL26 UBA52 UBA52 RPL36 RPL36 RPL22L1 RPL22L1 RPL26L1 RPL26L1 RPL31 RPL31 RPL32 RPL32 RPL12 RPL12 RPL39L RPL39L SEC61B SEC61B RPL21 RPL21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum; Belongs to the SEC61-beta family (96 aa)
RPL860S ribosomal protein L8; Component of the large ribosomal subunit (257 aa)
RPL3760S ribosomal protein L37; Binds to the 23S rRNA; L ribosomal proteins (97 aa)
RPL39LRibosomal protein L39 like; Belongs to the eukaryotic ribosomal protein eL39 family (51 aa)
TRUB1Probable tRNA pseudouridine synthase 1; May be responsible for synthesis of pseudouridine from uracil in transfer RNAs (349 aa)
SULT4A1Sulfotransferase 4A1; Atypical sulfotransferase family member with very low affinity for 3’-phospho-5’-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS; Sulfotransferases, cytosolic (284 aa)
RPL2160S ribosomal protein L21; Component of the large ribosomal subunit (160 aa)
RPL22L1Ribosomal protein L22 like 1; Belongs to the eukaryotic ribosomal protein eL22 family (122 aa)
RPL22Ribosomal protein L22; Belongs to the eukaryotic ribosomal protein eL22 family (128 aa)
RPL1260S ribosomal protein L12; Binds directly to 26S ribosomal RNA (165 aa)
DKC1H/ACA ribonucleoprotein complex subunit 4; Isoform 1- Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (’psi’) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the t [...] (514 aa)
MRPL2Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family (305 aa)
RPL3460S ribosomal protein L34; Component of the large ribosomal subunit (117 aa)
ERMNErmin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity) (297 aa)
RPL31Ribosomal protein L31 (128 aa)
UBA52Ubiquitin-60S ribosomal protein L40; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be invo [...] (128 aa)
RPL23A60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family (156 aa)
RPL9L ribosomal proteins (192 aa)
RPL32Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family (135 aa)
RPL35A60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site (110 aa)
RPL23Ribosomal protein L23 (140 aa)
RPL30Ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family (115 aa)
RPL26L1Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family (145 aa)
RPL26Ribosomal protein L26 (145 aa)
RPL3660S ribosomal protein L36; Component of the large ribosomal subunit (105 aa)
RPL2760S ribosomal protein L27; Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (136 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]