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PDCD2L | Programmed cell death protein 2-like; Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase (358 aa) | |||
TYROBP | TYRO protein tyrosine kinase-binding protein; Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin (113 aa) | |||
RHBDL2 | Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate- EFNB3; Rhomboid family (303 aa) | |||
ATP13A4 | Probable cation-transporting ATPase 13A4; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily (1196 aa) | |||
ATP13A5 | Probable cation-transporting ATPase 13A5; ATPase orphan transporters; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily (1218 aa) | |||
ATP13A1 | Manganese-transporting ATPase 13A1; Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily (1204 aa) | |||
SLC35B4 | UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily (331 aa) | |||
SLC18A1 | Chromaffin granule amine transporter; Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells; Belongs to the major facilitator superfamily. Vesicular transporter family (525 aa) | |||
ATP13A3 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters (1226 aa) | |||
PDCD2 | Programmed cell death protein 2; May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation; Zinc fingers MYND-type (344 aa) | |||
ENSG00000266953 | Uncharacterized protein (209 aa) | |||
CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1; Transcription factor involved in unfolded protein response (UPR). Binds the DNA consensus sequence 5’-GTGXGCXGC-3’. In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nuc [...] (519 aa) |